Medication info
Hanwha Lorkan Tablet 10/16mg (Rosuvastatin Calcium, Candesartan Cilexetil)

Hanwha Lorkan Tablet 10/16mg (Rosuvastatin Calcium, Candesartan Cilexetil)

Prescription medicationTablet경구
Ingredient · strength
Rosuvastatin Calcium›10.4mg / 1 tabletCandesartan Cilexetil›16mg / 1 tablet
Manufacturer / importer
한화제약(주)
Appearance
Yellow round film-coated tablet
Packaging
30 tablets (10 tablets/PTP X 3)
Approval status
Active

MFDS item code 202301657 · Approved 2023.05.24 · Insurance code 651602900

Summary

Main use
(Hypertension, Heart Failure) Improvement and (Hypercholesterolemia) Treatment
Who takes it
Adults · Children
Adult dose
Candesartan Cilexetil 1. Essential Hypertension - The recommended initial and maintenance dose is to take 8 to 16 mg orally once a day. - If blood pressure control is insufficient after four weeks at 16 mg once daily, it can be increased to a maximum of 32 mg once daily. - For patients with decreased effective blood volume, the initial dose is 4 mg, and for kidney impairment, begin at 4 mg and adjust as needed. - For liver impairment, the initial dose is 2 mg once daily.
Child dose
The safety and efficacy in children and adolescents (under 18 years) have not been established; therefore, there are no specific dosing instructions.

Ingredients

Manufacturer
한화제약(주)

Efficacy & effects

(Hypertension, Heart Failure) Improvement and (Hypercholesterolemia) Treatment

  • Essential hypertension
  • heart failure
  • impaired left ventricular systolic function
  • primary hypercholesterolemia
  • heterozygous familial hypercholesterolemia
  • combined hyperlipidemia
  • homozygous familial hypercholesterolemia
  • hypercholesterolemia
  • primary dysbetalipoproteinemia
  • increased high-sensitivity C-reactive protein
  • hypertension
  • low HDL cholesterol
View approved original text

This medication is used for patients who need to take both Candesartan Cilexetil and Rosuvastatin. Candesartan Cilexetil treats hypertension and aids heart failure patients with impaired left ventricular systolic function when there are restrictions on ACE inhibitors or additional therapy is needed. Meanwhile, Rosuvastatin is used with dietary therapy for patients with hypercholesterolemia or dyslipidemia to control cholesterol levels and slow the progression of arteriosclerosis. It may also reduce the risks of stroke, myocardial infarction, and vascular revascularization in patients at high risk of cardiovascular disease. Therefore, this medication improves hypertension and heart failure alongside cholesterol control and reduces cardiovascular disease risk.

How to take

Adult dose

Candesartan Cilexetil 1. Essential Hypertension - The recommended initial and maintenance dose is to take 8 to 16 mg orally once a day. - If blood pressure control is insufficient after four weeks at 16 mg once daily, it can be increased to a maximum of 32 mg once daily. - For patients with decreased effective blood volume, the initial dose is 4 mg, and for kidney impairment, begin at 4 mg and adjust as needed. - For liver impairment, the initial dose is 2 mg once daily.

Child dose

The safety and efficacy in children and adolescents (under 18 years) have not been established; therefore, there are no specific dosing instructions.

Precautions

This medication can cause serious harm to the fetus and newborn if administered to pregnant women, so it should be discontinued immediately if pregnancy is confirmed. Patients with allergic reactions to this medication, severely impaired liver function, pregnant or breastfeeding women, and those with certain kidney or muscle disorders should not use it. Elderly patients or those with mildly impaired liver function, high serum potassium levels, and others should use this medication cautiously, and regular checks of liver function and muscle health should be conducted during treatment. Muscle-related side effects such as muscle pain or weakness may occur, so if symptoms like muscle pain, cramps, or weakness appear, consult a doctor immediately. Additionally, since this medication may affect liver function, treatment should be stopped immediately if symptoms of hepatitis or jaundice occur, and medical attention should be sought. This medication can interact with other drugs, so anyone currently taking other medications should inform their doctor or pharmacist, particularly when combined with potassium-sparing diuretics, certain antibiotics, or antifungal medications. Women planning to become pregnant should consult a doctor before taking this medication and use appropriate contraceptive methods. Breastfeeding mothers should also avoid taking this medication. The safety and efficacy of this medication in children have not been established; therefore, its use is not recommended. In cases of overdose, appropriate treatment is required based on symptoms, and this medication is not removed by blood dialysis, so no specific detoxification method exists. Finally, this medication should be kept out of reach of children and stored in the original container to prevent misuse.

Side effects and when to seek care immediately

Serious side effects

Hives, angioedema, chest tightness, difficulty breathing, cold sweat, pallor, severe allergic reactions, severe rashes, blisters, peeling skin, pain in oral/ocular mucosa, severe dermatological reactions, shortness of breath or difficulty breathing, asthma attacks, respiratory irregularities accompanied by coughing and fever, yellowing of skin or eyes (jaundice), extreme fatigue, liver abnormalities (jaundice), sudden and severe headache, thunderclap headache, seizures

Mild side effects

  • Headache
  • dizziness
  • nasopharyngitis
  • lipoma
  • localized infection
  • periodontitis
  • fatigue
  • inflammation
  • foreign body sensation
  • itching
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  • generalized itching
  • dermatitis
  • musculoskeletal pain
  • neck pain
  • limb pain
  • cataracts
  • glare
  • dyspepsia
  • nausea
  • increased blood sugar
  • decreased serum sodium
  • hand fractures
  • hypoglycemia
  • nephrolithiasis
  • cough
  • tooth extraction
  • orthostatic dizziness
  • nausea
  • constipation
  • abdominal pain
  • diarrhea
  • loss of appetite
  • abdominal bloating
  • rash
  • weakness
  • arthralgia
  • muscle pain
  • C

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to avoid exposure to air or moisture. Additionally, it should be stored at room temperature between 1 to 30 degrees Celsius for optimal effectiveness.

Appearance and packaging

Appearance

Yellow round film-coated tablet

Package unit

30 tablets (10 tablets/PTP X 3)

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.