Coledi Injection (Cholecalciferol)

Adult administration

Adults receive 200,000 IU of cholecalciferol by intramuscular injection. Annual dosage must not exceed 600,000 IU of cholecalciferol.

Child administration

Adolescents receive 200,000 IU of cholecalciferol by intramuscular injection.

This medication is a supplement for vitamin D, and when used with foods fortified with vitamin D or other vitamin D preparations, it is essential to check the total vitamin D intake. Regular monitoring of calcium levels in blood and urine should be performed to ensure they do not exceed the normal range, and if calcium levels are too high, the medication should be discontinued. Ampoule injections pose a risk of glass fragments, so they should be handled carefully, especially in children and the elderly. This medication should not be used in patients with specific diseases or conditions, such as hypercalcemia, kidney stones, kidney dysfunction, pregnant or breastfeeding women. During treatment, various side effects may occur, including headaches, fatigue, muscle pain, digestive disturbances, dehydration, high blood pressure, and kidney problems. If any unusual symptoms occur, medical advice should be sought immediately. It is especially important to regularly check blood vitamin D levels and parathyroid hormone levels to maintain an appropriate dosage. Patients with weakened kidney function, the elderly, or those taking certain diuretics or heart medications should have regular kidney function tests, and medication dosages should be adjusted if necessary. This medication may interact with other drugs, so caution is advised when taken with anticonvulsants, steroids, certain diuretics, antacids, or warfarin. High doses should be avoided during pregnancy, and it is safer for pregnant and breastfeeding women not to use this medication. Safety and efficacy have not been established for children under 12 years of age, so its use is not recommended. In the case of overdose, medication should be discontinued immediately, calcium intake should be reduced, urine output should be increased, and adequate hydration should be maintained. This medication should not be mixed with other drugs, and it should be used quickly after opening, with any remaining medication discarded. When storing, protect from light and keep in a cool place with a temperature between 1 and 25 degrees Celsius to maintain medication effectiveness.

Serious side effects

Hypercalcemia, hypercalciuria, kidney impairment, tissue calcification in kidneys and blood vessels, arrhythmias, urticaria at the injection site.

Mild side effects

Headaches, weakness, fatigue, muscle pain, loss of appetite, weight loss, growth retardation, nausea, vomiting, constipation, diarrhea, polydipsia, polyuria, dehydration, high blood pressure, calcium stones, tissue calcification in kidneys and blood vessels, arrhythmias, mental symptoms, sensorium disturbances, joint pain, myasthenia, drowsiness, nitrogen retention, hypersensitivity reactions, thirst, confusion, gas bloat, abdominal pain, metallic taste, dry mouth, rash, itching, hypercalciuria, hypercalcemia, hyperphosphatemia,

This medication is sensitive to light, so it should be stored in a sealed container that blocks light. A cool place with a temperature between 1 and 25 degrees Celsius is suitable for storage. Proper storage will help maintain the effectiveness of the medication for a long time.

Appearance

A transparent liquid of light yellow color contained in a brown glass ampoule.

Package unit

1 milliliter per ampoule (1mL × 1, 5, 10 ampoules), 1.5 milliliter per ampoule (1.5mL × 1, 5, 10 ampoules)