Sitagliptin/Metformin Duo Tablet 50/850 mg

Adult dose

This medication is generally taken twice daily with food, and the dosage should be increased gradually to reduce gastrointestinal adverse effects caused by Metformin. 1. For patients who are currently not treated with Metformin: Take this medication 50/500 mg, 1 tablet twice daily. When increasing the dose, use 50/1000 mg, 1 tablet twice daily. 2. For patients receiving treatment with Metformin:

This medication contains Sitagliptin and Metformin and is primarily used for blood sugar control in patients with type 2 diabetes. Firstly, serious allergic reactions may occur during the use of this medication; if symptoms such as skin rash, difficulty breathing, or swelling of the face or neck occur, discontinue use immediately and consult a healthcare professional. Additionally, pancreatitis, which is inflammation of the pancreas, can rarely occur as a serious side effect; if severe abdominal pain, vomiting, or significant discomfort occurs, visit the hospital immediately. The Metformin component in this medication can cause a rare but fatal complication called lactic acidosis; if sudden muscle pain, weakness, difficulty breathing, or abdominal pain occurs, discontinue use immediately and seek emergency treatment. Patients with impaired kidney function or conditions that affect kidney function such as severe infections, dehydration, congestive heart failure, or acute myocardial infarction should not take this medication. Furthermore, pregnant women, women who may become pregnant, and nursing mothers should not take this medication. Patients with irregular or insufficient food intake, those who engage in vigorous exercise frequently, and those allergic to certain colorants should take this medication with caution. Hypoglycemic symptoms may occur during treatment; if symptoms such as dizziness, cold sweat, extreme hunger, or trembling appear, sugar should be taken immediately. The risk of hypoglycemia is higher, particularly when taking this medication with other hypoglycemic agents such as insulin or sulfonylureas. Before surgery or radiographic examinations using contrast agents, inform healthcare providers about the use of this medication, and if necessary, temporarily discontinue use. Regular tests of liver or kidney function should be conducted, and if abnormalities are found, dosage adjustments or discontinuation may be necessary. Excessive alcohol consumption should be avoided while using this medication, as alcohol intake may increase the risk of lactic acidosis. Finally, if new symptoms or adverse reactions occur while taking this medication, it is important to immediately inform and consult with a healthcare provider.

Serious side effects

Hives, severe hypersensitivity reactions (including anaphylaxis, angioedema, Stevens-Johnson syndrome), acute pancreatitis (hemorrhagic or necrotizing pancreatitis, fatal/non-fatal), severe lactic acidosis, hypoglycemia, difficulty breathing, acute kidney failure, liver anomalies (elevation of liver enzymes), bullous pemphigoid, severe hypoglycemia, severe edema, acute kidney failure, severe skin reactions (severe rash, blisters, skin peeling, pain in oral/ocular mucosa), severe

Mild side effects

• Diarrhea
• nausea
• vomiting
• abdominal pain
• headache
• upper respiratory infection
• nasopharyngitis
• constipation
• muscle pain
• limb pain

This medication should be stored in a tightly sealed container to prevent air or moisture from entering and kept at room temperature between 1 to 30 degrees Celsius. Proper temperature and environment maintenance will help preserve the effectiveness and safety of the medication.

Appearance

Pink oval film-coated tablets

Package unit

Bottle - 100 tablets/bottle, Bottle - 30 tablets/bottle