Janudime Tablets 50/500mg

Adult dose

This medication is typically taken twice a day with meals, and the dosage should be gradually increased to reduce gastrointestinal side effects caused by metformin. 1. Patients not previously treated with metformin: The initial dosage of this medication 50/500 mg is taken twice daily, one tablet each time, with the option to increase to 50/1000 mg taken twice daily, one tablet each time. 2. Patients currently receiving metformin treatment: Sitagliptin 50 mg

This medication is used for diabetes treatment and contains two components. The first component helps to control blood sugar levels but may cause serious allergic reactions or skin disorders in some patients. If these symptoms occur, discontinue the medication immediately and consult a physician. Furthermore, during the use of this medication, inflammation of the pancreas, known as pancreatitis, may occur; therefore, symptoms such as abdominal pain or vomiting should be carefully monitored, and if suspected, medication should be discontinued. The second component is effective in lowering blood sugar but could lead to a dangerous metabolic disorder called lactic acidosis in severe cases; therefore, patients with reduced kidney function or liver disease should not take this medication. This medication is not to be administered to patients with impaired kidney function, those in severe conditions such as acute heart failure or acute myocardial infarction, pregnant or breastfeeding women, or children under the age of 18. Additionally, regular meals and appropriate exercise are required while taking this medication, and attention should be paid to hypoglycemic symptoms. There may be an increased risk of hypoglycemia when taken with other blood glucose-lowering agents. This medication may occasionally cause side effects such as diarrhea, nausea, vomiting, headache, upper respiratory infections, so if symptoms are severe or persist, consult a physician. Discontinue this medication temporarily before and after surgery and resume only after normal kidney function is restored. Excessive alcohol consumption may increase the risk of side effects from this medication, so it is advisable to avoid alcohol while taking it. Regular kidney function and blood tests should be conducted during treatment, and tests for vitamin B12 deficiency may also be necessary. Moreover, this medication contains certain coloring agents, so caution is needed for those allergic to such components. In case of overdose, seek medical attention immediately for appropriate treatment, and if necessary, blood dialysis can be performed to remove the medication.

Serious side effects

Urticaria, angioedema, anaphylaxis, Stevens-Johnson syndrome, severe swelling (edema), rash, cutaneous vasculitis, exfoliative skin disease, severe allergic reactions; acute pancreatitis (including fatal/non-fatal hemorrhagic or necrotizing pancreatitis), elevated liver enzymes, acute renal failure, respiratory distress; severe joint pain accompanied by disability, bullous pemphigoid, rhabdomyolysis; acute renal failure, unstable angina; lactic acidosis (severe metabolic acidosis)

Mild side effects

Diarrhea, upper respiratory infection, headache, nausea, vomiting, abdominal pain, constipation, nasopharyngitis, myalgia, limb pain, back pain, pruritus, thrombocytopenia, rhabdomyolysis, itching, dizziness, decreased appetite, weight loss, mental illness (anorexia), metabolic and nutritional disorders (weight loss)

This medication should be stored in a tightly sealed container that is well-ventilated, and it is advisable to keep it at a temperature ranging between 1 to 30 degrees Celsius. Proper storage maintains the medication's effectiveness and prevents deterioration.

Appearance

Bright pink oval film-coated tablet

Package unit

Bottle - 100 tablets/bottle, Bottle - 30 tablets/bottle