Danumet Tablet 50/500 mg

Adult dose

This medicine is generally taken 2 times a day with food, and the dosage is gradually increased to reduce gastrointestinal side effects caused by metformin. 1. For patients not currently being treated with metformin: Take 50/500 mg of this medicine 1 tablet twice daily, and if necessary, it can be increased to 50/1000 mg, 1 tablet twice daily. 2. For patients currently receiving treatment with metformin:

This medicine consists of two components and helps in controlling blood sugar. Firstly, the sitagliptin component can rarely cause serious allergic reactions, so if symptoms such as rash or difficulty breathing occur, the medication should be discontinued immediately. Additionally, there is a risk of pancreatitis, which is inflammation of the pancreas, so if there are any symptoms like abdominal pain, vomiting, or severe abdominal pain, consulting a doctor immediately is recommended. The metformin component can cause a rare but life-threatening condition known as lactic acidosis. This condition can present symptoms such as muscle pain, fatigue, difficulty breathing, and abdominal pain, so treatment should be sought immediately if these symptoms occur. This medicine should not be used in patients with moderate to severe renal impairment, severe infections, congestive heart failure, or acute myocardial infarction. It is also contraindicated in pregnant or breastfeeding women. While taking this medicine, renal function should be checked regularly, and if there is dehydration or severe vomiting or diarrhea, the medication should be temporarily discontinued and a doctor consulted. This medicine can cause hypoglycemia, particularly when taken with other hypoglycemic agents, so symptoms of hypoglycemia such as dizziness, sweating, and trembling should be monitored closely. It is advisable to avoid alcohol consumption during treatment with this medicine, and the medication should be temporarily discontinued prior to surgery or radiologic contrast studies. Lastly, some individuals may experience side effects such as diarrhea, headache, upper respiratory infections, so if these symptoms are severe, consulting a doctor is advisable.

Serious side effects

Hives, angioedema, chest tightness, shortness of breath, cold sweat, pallor, severe allergic reactions, severe rash accompanied by high fever, blisters, skin peeling, mucosal pain in the mouth/eyes, severe cutaneous adverse reactions, difficulty breathing or shortness of breath, asthma attacks, respiratory distress accompanied by cough + fever, liver dysfunction (jaundice), sudden and very severe headache, thunderclap headache, seizures, confusion, vision disturbances, paralysis, severe kidney impairment

Mild side effects

• Diarrhea
• upper respiratory infection
• headache
• nausea
• vomiting
• abdominal pain
• constipation
• nasopharyngitis
• muscle pain
• limb pain

This medicine should be stored in a tightly sealed container to protect it from air and moisture, and it is best to keep it at room temperature between 1 to 30 degrees Celsius. Proper storage can help maintain the effectiveness of the drug for a longer duration.

Appearance

Light pink oval film-coated tablet

Package unit

Bottle - 100 tablets/bottle, Bottle - 30 tablets/bottle