Biflex Dual Care Tablet

Adult dose

For individuals 12 years and older: Take 1 tablet once daily after meals

This medication should not be taken by patients with hypercalcemia (excessive calcium in the blood) or sarcoidosis (an unknown systemic inflammatory disease), or those with kidney disorders. Additionally, individuals with allergic reactions to this medication or its ingredients, infants under 12 months, kidney stone patients, and those with severe renal failure symptoms should also avoid taking this medication. During the use of this medication, it is important to avoid taking drugs such as phosphates, calcium salts, oral tetracycline preparations, antacids, and levodopa together. Infants under 1 year, patients currently receiving medical treatment, children exposed to sunlight with a normal diet, pregnant women or women with potential pregnancy, lactating mothers, premature infants, and children should consult with a physician or pharmacist before taking this medication. Particularly, caution is necessary because the vitamin D component can be transmitted to newborns through breast milk, potentially causing hypercalcemia. Patients with gastrointestinal diseases such as peptic ulcers, chronic ulcerative colitis, or localized colitis, those with heart or circulatory function issues, kidney disorders, individuals with hypoproteinemia, people using cardiac glycosides, patients with a history of kidney stones, and pregnant women should also consult a specialist before taking this medication. If symptoms such as nausea, vomiting, diarrhea, oral inflammation, loss of appetite, abdominal bloating, constipation, hypotension, facial flushing, skin rashes, irregular heartbeats, cardiac arrest, central nervous system dysfunction, dermatitis, foul smell during sweating or breathing, hair loss, restlessness, gastrointestinal disturbances, abdominal pain, or pulmonary edema occur, immediately stop taking the medication and consult a specialist. Additionally, prolonged high-dose intake of pyridoxine can lead to neurological issues, and overdose of vitamin B12 can result in blood abnormalities, thus caution is needed. High-dose intake may worsen gastric ulcers, cause disturbances in glucose metabolism, elevate uric acid levels in the bloodstream, or lead to liver damage; excessive intake may result in symptoms such as nausea, vomiting, hypernatremia, congestive heart failure, and edema. Long-term use can lead to hypercalcemia and nephrolithiasis, so caution is necessary, and if taken alongside certain diuretics, there is a risk of hyperkalemia, requiring specialist consultation. If overdosed or if symptoms do not improve after one month of use, it is necessary to seek immediate consultation with a specialist. When taking this medication, it is essential to adhere to the prescribed dosage and administration methods, and when administering it to children, it should be done under the guidance and supervision of a guardian. This medication may change the color of urine to yellow, affecting clinical test results, so note this. It is advisable to avoid drinking tea containing tannins, such as green tea or black tea, during and before taking this medication. Store this medication out of reach of children, away from direct sunlight, and in a cool, dry, and airtight place. Moreover, to prevent misuse and maintain quality, do not transfer medication to other containers.

Serious side effects

• Irregular heartbeat
• cardiac arrest (cardiac stoppage)
• hypercalcemia
• nephrolithiasis
• hypernatremia
• congestive heart failure
• edema

Mild side effects

• Nausea
• vomiting
• diarrhea
• loose stools
• stomatitis (oral inflammation)
• loss of appetite
• abdominal bloating
• constipation
• hypotension
• facial flushing

Drug interactions

This medication should not be taken with phosphates, calcium salts, oral tetracycline preparations, antacids, or levodopa. Caution is also warranted when combined with antagonists of aldosterone or triamterene, as it may cause hyperkalemia.

Food interactions

This medication should not be taken with teas containing tannins, such as green tea and black tea. It is advisable to avoid such beverages during and before taking this medication.

This medication may be sensitive to air and moisture, so it should be stored in an airtight container. It is best to maintain a storage temperature between 1 to 30 degrees Celsius at room temperature. By storing it this way, the effectiveness of the medication can be preserved for a longer period.

Appearance

Oval film-coated tablets in reddish-brown color

Package unit

60 tablets/bottle, 120 tablets/box [(60 tablets/bottle X 2)]