Dik Double M Tablet 10/4 mg (Dapagliflozin, Glimepiride)

Adult dose

This medication may be administered as one tablet (10 mg dapagliflozin/4 mg glimepiride) once daily just before breakfast or the first meal for patients prescribed glimepiride 4 mg and dapagliflozin 10 mg. The tablet must be swallowed whole.

This medication should not be taken by certain patients. Patients with allergies to the main ingredients, excipients, or sulfonylureas should not take this medication. Patients with type 1 diabetes or those who have experienced diabetic ketoacidosis or coma should not use this medication. Additionally, it contains anhydrous lactose, which may pose risks to those with lactose intolerance or certain genetic issues. Patients with severe kidney or liver dysfunction, as well as pregnant or breastfeeding women, should not take this medication. Patients with severe infections or those before and after surgery, as well as those with severe trauma, should avoid use, and those with gastrointestinal disorders should be cautious due to the risk of hypoglycemia. Dialysis patients should also refrain from using this medication. Special caution is required when administering this medication to patients with reduced fluid volume or kidney function impairments. Blood pressure drops or worsening kidney function may occur, so it's essential to carefully monitor fluid status and kidney function before and during administration. For patients with severely compromised kidney function, the blood sugar control effect may be diminished, and its use is not recommended. Furthermore, one of the ingredients in this medication poses a risk of hypoglycemia, so careful monitoring of blood sugar levels is essential at the onset of treatment. Special caution is advised for the elderly, individuals with poor nutritional status or irregular eating habits, those with high alcohol consumption, and patients with impaired kidney or liver function, as they are at higher risk of hypoglycemia. If symptoms of hypoglycemia occur, immediate consultation with healthcare providers is necessary, and dosage adjustments may be required. While taking this medication, urinary and genital infections may occur, so immediate treatment is necessary if infection symptoms appear. Dehydration or hypotension symptoms due to reduced fluid volume may also occur, so any symptoms like dizziness or light-headedness should be reported to healthcare providers. Women who are pregnant or may become pregnant, as well as those who are breastfeeding, should not take this medication, and if pregnancy is confirmed, it should be discontinued immediately. Safety and efficacy for children and adolescents under 18 years have not been established, so use in this population is not advised. In cases of overdose, symptoms such as hypoglycemia or dehydration may appear, and immediate medical attention should be sought. Awareness of hypoglycemia risk during treatment is crucial, especially when driving or operating machinery. The medication should be stored out of reach of children and kept sealed in its original container.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attacks, cough accompanied by fever or respiratory distress, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination

Mild side effects

Hypoglycemia, dizziness, constipation, dry mouth, back pain, dysuria, polyuria, nocturia, increased hematocrit, decreased initial renal creatinine clearance, dyslipidemia, increased serum creatinine, increased blood urea, weight loss, dehydration, hypovolemia, hypotension, vulvovaginitis, balanitis, fungal infections, urinary tract infections, itching, cold sweat, dermatitis, dry skin, hyperkeratosis, skin lesions, muscle weakness, chest pain, asthenia,

This medication should be stored in a tightly sealed container to avoid exposure to air or moisture. It is also important to maintain its efficacy by storing it at room temperature, between 1 and 30 degrees Celsius.

Appearance

Yellow oval film-coated tablets

Package unit

Box - 28 tablets/box [14 tablets/PTP×2], bottle - 30 tablets/bottle, bottle - 300 tablets/bottle, bottle - 1000 tablets/bottle