Medication info
Alprazolam 0.5 mg Tablet (Alprazolam)

Alprazolam 0.5 mg Tablet (Alprazolam)

Prescription medicationTabletOral
Ingredient · strength
Alprazolam›0.5mg / 1 tablet
Manufacturer / importer
Hana Pharmaceutical Co., Ltd.
Appearance
Light orange oval tablet
Packaging
30 tablets/bottle, 100 tablets/bottle
Approval status
Active

MFDS item code 202300714 · Approved 2023.02.28 · Insurance code 657807880

Summary

Main use
Relief of symptoms of anxiety disorders, anxiety accompanying depression, panic disorder, and psychosomatic disorders
Who takes it
Adults
Adult dose
To achieve maximum benefit, determine the dose individually. The usual daily doses listed below are appropriate for most patients, but higher doses may be required. In such cases, increase the dose gradually to avoid adverse effects. The risk of dependence may increase with the dose and duration of treatment. Therefore, administer the lowest effective dose for the shortest possible duration and frequently reassess the need for continued treatment. ○ Adults 1. The initial dose of alprazolam is 0.25-0.5㎎ per dose 3 times daily, with a maximum dose of 4㎎ per day. For elderly patients, patients with hepatic impairment, and debilitated patients, the initial dose is 0.25㎎ per dose 2-3 times daily. Reduce the dose if adverse effects occur at the initial dose. 2. Psychosomatic disorders Administer 1.2㎎ per day of this medicine orally in 3 divided doses. If increasing the dose, increase gradually to a maximum of 2.4㎎ per day and administer orally in 3-4 divided doses. For elderly patients, the initial dose is 0.4㎎ per dose 1-2 times daily, with a maximum dose of 1.2㎎ per day. 3. Panic disorder The initial dose of this medicine is 0.5㎎. Depending on the patient's response to treatment, increase the dose by no more than 1㎎ at intervals of 3-4 days, to an average daily dose of 5-6㎎, administered in 3-4 divided doses. When discontinuing treatment, reduce the dose by no more than 0.5㎎, usually at 3-day intervals; an even lower dose may be required.

Ingredients

Manufacturer
Hana Pharmaceutical Co., Ltd.

Efficacy & effects

Relief of symptoms of anxiety disorders, anxiety accompanying depression, panic disorder, and psychosomatic disorders

  • Anxiety disorders
  • anxiety symptoms
  • anxiety accompanying depression
  • anxiety in psychosomatic disorders
  • tension
  • depression
  • sleep disorders
  • panic disorders
View approved original text

This medicine is used for the treatment of anxiety disorders and for the short-term relief of anxiety symptoms. It is also helpful in alleviating anxiety symptoms associated with depression. It is effective for anxiety, tension, depression, and sleep disorders related to psychosomatic disorders. In particular, it alleviates symptoms that occur in conditions such as gastric and duodenal ulcer, irritable bowel syndrome, and autonomic dysfunction. It is used to treat panic disorders to help stabilize the patient's mental state and is generally used to improve various symptoms associated with anxiety.

How to take

Adult dose

To achieve maximum benefit, determine the dose individually. The usual daily doses listed below are appropriate for most patients, but higher doses may be required. In such cases, increase the dose gradually to avoid adverse effects. The risk of dependence may increase with the dose and duration of treatment. Therefore, administer the lowest effective dose for the shortest possible duration and frequently reassess the need for continued treatment. ○ Adults 1. The initial dose of alprazolam is 0.25-0.5㎎ per dose 3 times daily, with a maximum dose of 4㎎ per day. For elderly patients, patients with hepatic impairment, and debilitated patients, the initial dose is 0.25㎎ per dose 2-3 times daily. Reduce the dose if adverse effects occur at the initial dose. 2. Psychosomatic disorders Administer 1.2㎎ per day of this medicine orally in 3 divided doses. If increasing the dose, increase gradually to a maximum of 2.4㎎ per day and administer orally in 3-4 divided doses. For elderly patients, the initial dose is 0.4㎎ per dose 1-2 times daily, with a maximum dose of 1.2㎎ per day. 3. Panic disorder The initial dose of this medicine is 0.5㎎. Depending on the patient's response to treatment, increase the dose by no more than 1㎎ at intervals of 3-4 days, to an average daily dose of 5-6㎎, administered in 3-4 divided doses. When discontinuing treatment, reduce the dose by no more than 0.5㎎, usually at 3-day intervals; an even lower dose may be required.

Precautions

This medication is a benzodiazepine and has sedative effects, influencing the central nervous system, and is used for anxiety relief or to improve sleep. Taking this medication with narcotics can lead to respiratory depression, severe sedation, coma, or even death, so it should only be taken at the minimum dosage for a short period when absolutely necessary. This drug has a risk of abuse and dependency, so it should be strictly managed under a doctor's instruction during use, and any remaining medication should be stored safely and disposed of to prevent misuse. Patients with certain conditions, such as acute narrow-angle glaucoma, severe myasthenia gravis, severe respiratory failure, severe liver failure, sleep apnea patients, or individuals with drug or alcohol dependency should not take this medication. Patients with weakened heart, liver, kidney function, the elderly, or those with brain injury should be particularly cautious when taking this medication, as it contains ingredients that can cause allergic reactions in sensitive individuals. Drowsiness, decreased concentration, and reduced reflexes may occur while taking this medication, so driving or operating dangerous machinery should be avoided. Long-term use may require regular health check-ups, such as liver function tests. Suddenly stopping this medication can lead to withdrawal symptoms, so the dosage should be gradually reduced according to a doctor's instructions. Taking it with other central nervous system depressants or alcohol may enhance the sedative effects and can be dangerous, so co-administration should be avoided or discussed with a doctor. It should not be taken during pregnancy, especially in later stages, as it may affect the fetus, and caution is advised while breastfeeding, as it can affect the baby through breast milk. It is recommended not to use in children or adolescents under 18 years as safety and efficacy have not been established. In cases of overdose, dangerous symptoms such as severe drowsiness, coma, and respiratory depression may appear, and emergency treatment should be sought immediately. This medication should be stored out of reach of children and kept in its original packaging to prevent deterioration and misuse.

Side effects

  • Mild discomfort
  • insomnia
  • abdominal and muscle cramps
  • vomiting
  • sweating
  • tremors
  • convulsions
  • seizures
  • agitation
  • increased muscle rigidity
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  • sleep disturbances
  • hallucinations
  • anxiety
  • anger
  • drug dependence
  • hypomania
  • aggression
  • hostility
  • abnormal thoughts
  • movement disorders
  • substance abuse
  • sedation
  • drowsiness
  • ataxia
  • memory impairment
  • dysarthria
  • dizziness
  • headache
  • balance disorders
  • coordination disorders
  • attention disorders
  • hypersomnia
  • somnolence
  • tremors
  • amnesia
  • autonomic nervous system imbalance
  • muscle tone abnormalities
  • blurred vision
  • constipation
  • dry mouth
  • nausea
  • gastrointestinal disturbances
  • hepatitis
  • liver dysfunction
  • jaundice
  • dermatitis
  • angioedema
  • photosensitivity reactions
  • muscle weakness
  • urinary incontinence
  • urinary retention
  • sexual dysfunction
  • menstrual irregularities
  • fatigue
  • hypersensitivity
  • drug withdrawal syndrome
  • peripheral edema
  • weight loss
  • weight gain
  • increased intraocular pressure
  • drowsiness
  • mild headache
  • depression
  • confusion
  • insomnia
  • nervousness
  • syncope
  • dizziness
  • inability to sit still
  • thirst
  • diarrhea
  • increased salivation
  • tachycardia
  • palpitations
  • hypotension
  • nasal congestion
  • disturbances
  • tremors
  • dermatitis
  • rash
  • increased appetite
  • decreased appetite
  • urinary disorders
  • menstrual disorders
  • sexual dysfunction
  • edema
  • infection
  • hallucinations
  • depersonalization
  • taste changes
  • double vision
  • increased bilirubin
  • increased liver enzymes
  • jaundice
  • orientation disturbances
  • ataxia
  • balance disorders
  • difficulty concentrating
  • hypersomnia
  • somnolence
  • muscle weakness
  • seizures
  • slurred speech
  • jaundice
  • musculoskeletal weakness
  • itching
  • double vision
  • dysarthria
  • changes in libido
  • menstrual irregularities
  • urinary incontinence
  • urinary retention
  • insomnia
  • involuntary movement disorders
  • cognitive impairment
  • disinhibition
  • sensory disturbances
  • polyuria
  • vasomotor disorders
  • unreality
  • bizarre dreams
  • fear
  • warm sensations
  • decreased salivation
  • abdominal discomfort
  • chest pain
  • hyperventilation
  • upper respiratory tract infection
  • tinnitus
  • muscle cramps
  • muscle rigidity
  • sweating
  • rash
  • increased appetite
  • decreased appetite
  • weight gain
  • weight loss
  • urinary disorders
  • menstrual disorders
  • sexual dysfunction
  • edema
  • urinary incontinence
  • infection
  • delirium
  • apathy
  • hyperactivity
  • dyspepsia
  • asthenia
  • chest pain
  • malaise
  • falling

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a sealed container to avoid exposure to air and light, ideally in a cool place between 1 and 30 degrees Celsius. Storing it away from direct sunlight will help maintain its effectiveness longer.

Appearance and packaging

Appearance

Light orange oval tablet

Package unit

30 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.