DapaDucita Tablets 10/100 mg (Dapagliflozin Propanediol Hydrate, Sitagliptin Phosphate Hydrate)

Adult dosage

For patients taking 100 mg of sitagliptin and 10 mg of dapagliflozin, 1 tablet may be taken once daily regardless of meals. The tablet should be swallowed whole.

This medication may cause rare but serious allergic reactions due to the sitagliptin component. If symptoms like skin rash, difficulty breathing, or swelling of the face or neck occur within three months of use, discontinue immediately and consult a doctor. This drug carries a risk of pancreatitis, which is inflammation of the pancreas; immediate medical attention is required if symptoms such as abdominal pain, vomiting, or loss of appetite arise. This drug should not be used in patients with type 1 diabetes, diabetic ketoacidosis, or those undergoing dialysis. In patients with decreased fluid volume or impaired kidney function, there may be a risk of lowered blood pressure or worsening kidney function. Therefore, solid evaluation of fluid status and kidney function is recommended before starting this medication, and symptoms and kidney function should be monitored periodically during treatment. The efficacy of this drug in lowering blood sugar can vary depending on kidney function, and it is not recommended for patients with severely impaired kidney function. This medication may increase the risk of genital infections and urinary tract infections. If symptoms of infection occur, seek treatment immediately; patients with a history of infections should exercise additional caution. This drug may cause hypoglycemia, particularly when taken with insulin or sulfonylureas, so one should be vigilant for signs of low blood sugar and may need to adjust the dosage of these medications accordingly. This drug can lead to serious metabolic abnormalities like dehydration, hypotension, and ketoacidosis, so if symptoms such as vomiting, nausea, abdominal pain, or difficulty breathing occur, consult healthcare professionals immediately. Women who are pregnant or breastfeeding should avoid using this medication, and it should be discontinued immediately if pregnancy is confirmed. Elderly patients or those with decreased kidney function should regularly monitor their kidney function before and during the use of this drug. In case of overdose, as there is no specific antidote, appropriate treatment based on symptoms should be administered, and procedures like dialysis may be considered if necessary. This drug requires caution when driving or operating machinery, especially due to the potential for hypoglycemic symptoms. The safety and efficacy of this drug have not been established in children, so it is not to be used in individuals under 18 years old. Store this medication in its original container and keep it out of reach of children.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweats, pallor, anaphylaxis, angioedema, exfoliative skin disorders, Stevens-Johnson syndrome, acute pancreatitis, fatal/non-fatal hemorrhagic or necrotizing pancreatitis, severe allergic reactions, severe dermatological reactions, respiratory issues, jaundice (yellowing of skin or eyes), pronounced lethargy, liver abnormalities (jaundice), sudden and severe headache.

Mild side effects

• Vulvovaginitis
• balanitis
• genital infections
• urinary tract infections
• decreased fluid volume
• thirst
• hypoglycemia
• dizziness
• constipation
• dry mouth

This medication should be stored in a tightly sealed container to protect it from air and moisture, at room temperature between 1 and 30 degrees Celsius. Storing it this way helps maintain the drug's efficacy and allows for safe use.

Appearance

Beige oval film-coated tablets

Package unit

PTP - 30 tablets/PTP [10 tablets/PTP x 3]