Sitabiang Duo XR Controlled-release Tablets 100/1000 mg

Adult dose

The dosage of this medication 100/1000 mg controlled-release tablets is 1 tablet once a day. Patients taking this medication 50/500 mg controlled-release or 50/1000 mg controlled-release tablets should take 2 tablets simultaneously once a day. 1. For patients currently not treated with metformin: The initial dose of this medication is a total daily amount of 100 mg of sitagliptin and 1000 mg of metformin. Initial dosage.

This medication is a combination of sitagliptin and metformin, used for diabetes treatment. Firstly, the sitagliptin component can cause rare but serious allergic reactions. These reactions may include anaphylaxis, angioedema, and serious skin disorders, so if skin rashes, difficulty breathing, swelling of the face or neck occur within 3 months after taking the medication, stop taking it immediately and consult a doctor. Additionally, sitagliptin can cause pancreatitis, which is inflammation of the pancreas, so if sudden abdominal pain, nausea, vomiting, or other symptoms appear, stop taking the medication immediately and seek medical attention. The metformin component can cause a rare side effect known as lactic acidosis, which is a very dangerous condition that requires prompt treatment. Therefore, this medication should not be taken by patients with impaired kidney function or those with certain conditions such as severe infections, dehydration, or heart failure. This medication should not be administered to patients with moderately impaired kidney function or worse, patients with acute heart failure, patients receiving radiological contrast agents, type 1 diabetes patients, or women who are pregnant or breastfeeding. Moreover, caution should be exercised while taking this medication in cases of irregular meals, vigorous exercise, and interactions with certain drugs, as it contains Red 40, which may cause allergic reactions in sensitive individuals. During treatment, gastrointestinal disturbances, hypoglycemia, or skin rashes may occur, so consult a doctor if symptoms are severe or concerning. Finally, temporarily stopping the medication before and after surgery or in cases of severe infections or trauma is required, and it can be resumed once the condition stabilizes.

Serious side effects

• Severe hypersensitivity reactions: Including anaphylaxis, angioedema, and Stevens-Johnson syndrome involving exfoliative skin disorders.
• Acute pancreatitis (including hemorrhagic or necrotizing).
• Severe lactic acidosis and risk of hypoglycemia.
• Hypersensitivity reactions such as anaphylaxis or angioedema.
• Liver dysfunction and risk related to lactic acidosis.

Mild side effects

Gastrointestinal side effects (indigestion, nausea, diarrhea, etc.).

This medication should be stored in a tightly closed container to prevent exposure to air and moisture. The storage temperature should be maintained between 1 degree and 30 degrees Celsius at room temperature. This will help preserve the medication's effectiveness for a longer period.

Appearance

Light blue, bilaterally convex oval-shaped controlled-release film-coated tablets

Package unit

Bottle - 100 tablets/bottle, Bottle - 30 tablets/bottle