Sitagliptin and Dapagliflozin 10/100 milligrams

Adult dosage

For patients receiving sitagliptin 100 mg and dapagliflozin 10 mg, take one tablet once daily regardless of meals. The tablet must be swallowed whole.

This medication can lead to rare but serious allergic reactions after administration; if symptoms such as skin rash, swelling, or difficulty breathing occur, discontinue use immediately and consult a physician. This medication may cause pancreatitis and related conditions; inform healthcare personnel immediately if abdominal pain, vomiting, or persistent abdominal discomfort occurs. This medication should not be used in patients with allergies to certain ingredients, those with type 1 diabetes, diabetic ketoacidosis, or those who are on dialysis. Patients with reduced kidney function or elderly patients require careful management, including dosage adjustments or kidney function assessments prior to administration. This medication may cause side effects such as reduced fluid volume, hypotension, and hypoglycemia; therefore, careful monitoring of symptoms is especially important when taking antihypertensive medications. There may be an increased risk of genital and urinary tract infections, so prompt treatment is necessary if infection symptoms appear, especially in patients with a history of infections. Women who are pregnant or breastfeeding are advised to avoid using this medication, and it should be discontinued immediately upon confirmation of pregnancy. During treatment with this medication, caution is necessary while driving or operating machinery because of the potential risk of accidents due to hypoglycemia. In the case of overdose, there is no specific antidote, so it is essential to visit a medical institution immediately for appropriate symptomatic treatment.

Serious side effects

Urticaria, angioedema, anaphylaxis, exfoliative skin diseases including Stevens-Johnson syndrome, acute pancreatitis, hemorrhagic or necrotizing pancreatitis, severe hypoglycemia, severe allergic reactions, severe skin adverse reactions, dyspnea, asthma attacks, seizures, altered consciousness, vision changes, paralysis, jaundice, liver abnormalities, acute kidney injury, kidney dysfunction, renal failure, reduced fluid volume, hypotension, severe edema, uroseptic shock, kidney-related issues

Mild side effects

• Upper respiratory infections
• nasopharyngitis
• headache
• constipation
• dry mouth
• lumbago
• polyuria
• nocturia
• thirst
• weight loss

This medication is sensitive to air and moisture, so it must be stored in a tightly sealed container. The storage temperature should be maintained between 1 and 30 degrees Celsius to preserve the medication's efficacy and safety.

Appearance

Beige, oval-shaped film-coated tablets

Package unit

30 tablets/PTP [10 tablets/PTP X 3]