Posia Tablets 10/100 Milligrams (Dapagliflozin, Sitagliptin)

Adult dosage

This medication is administered once daily at a dose of 1 tablet containing sitagliptin 100 mg and dapagliflozin 10 mg, regardless of meals. The tablet should be swallowed whole.

This medication may cause severe allergic reactions due to the sitagliptin component; therefore, if symptoms such as skin rash, difficulty breathing, or swelling of the face or neck occur after taking it, immediately discontinue use and consult a physician. Additionally, this medication may cause serious pancreatic inflammation known as pancreatitis during use, so if symptoms such as abdominal pain, vomiting, or nausea arise, promptly inform medical personnel. This medication should not be administered to patients with type 1 diabetes, diabetic ketoacidosis, or those undergoing dialysis. Use with caution in patients with reduced fluid volume or renal dysfunction, particularly in elderly patients or those on diuretics, who should be closely monitored for hypotension or dehydration symptoms. Dose adjustment may be required for patients with reduced kidney function, and regular kidney function tests should be conducted before and during treatment. There may be an increased risk of genital infections and urinary tract infections during use; thus, rapid treatment should be sought if infection symptoms arise. Moreover, caution is warranted for hypoglycemia risk when taken with other hypoglycemic agents such as insulin or sulfonylureas, and dosage adjustment of those medications may be necessary as needed. Pregnant or breastfeeding women are advised not to take this medication, and if pregnancy is confirmed, use should be immediately discontinued. This medication should not be used in patients under 18 years of age as safety and efficacy have not been established. In cases of overdose, as there are no specific antidotes, appropriate treatment according to symptoms should be sought, and hospital observation and treatment may be required if necessary. Lastly, caution is advised during driving or operating machinery as there may be risks of hypoglycemia during use of this medication.

Serious side effects

Hives, severe swelling, chest tightness, difficulty breathing, cold sweat, pallor, severe hypersensitivity reactions, anaphylaxis, angioedema, Stevens-Johnson syndrome, exfoliative dermatitis, acute pancreatitis, life-threatening hemorrhagic or necrotizing pancreatitis, severe allergic reactions, acute kidney injury, hypotension, renal impairment, diabetic ketoacidosis, ketosis, urosepticemia, pyelonephritis, rash, severe skin adverse reactions, headache

Mild side effects

• Headache
• dizziness
• thirst
• constipation
• dry mouth
• back pain
• dysuria
• polyuria
• nocturia
• fainting

This medication may be sensitive to air and moisture and should be stored in a tightly closed container. It is important to maintain a storage temperature between 1 and 30 degrees Celsius (room temperature) to ensure the medication's effectiveness.

Appearance

Beige oval film-coated tablet

Package unit

30 tablets/PTP [10 tablets/PTP (Alu-Alu) x 3]