Esplo Tablet 10/100 mg

Adult dosage

This medication can be administered at a dose of 1 tablet once a day without regard to meals to patients receiving sitagliptin 100 mg and dapagliflozin 10 mg. The tablets should be swallowed whole.

This medication contains sitagliptin and dapagliflozin, and is primarily used for blood glucose control in patients with type 2 diabetes. Firstly, this medication can cause hypersensitivity reactions, so patients who have had allergic reactions to this medication or its components should not take it. Moreover, serious pancreatic disorders such as acute pancreatitis have been reported, so if symptoms such as abdominal pain or dyspepsia occur while taking this medication, a doctor should be consulted immediately. This medication may affect kidney function, so patients with impaired renal function need dose adjustments, and it should not be administered to patients undergoing dialysis. Dapagliflozin may cause decreased fluid volume and hypotension, thus elderly patients or those taking diuretics or with a history of hypotension should exercise caution. This medication may also increase the risk of genital and urinary tract infections, so prompt treatment is necessary if there are related symptoms. Serious metabolic disturbances such as diabetic ketoacidosis may occur, so if symptoms such as vomiting, abdominal pain, or shortness of breath arise, healthcare personnel should be notified immediately. Use of this medication is not recommended for pregnant or breastfeeding women, especially during breastfeeding as the drug may be passed into breast milk, so it should be avoided. The risk of hypoglycemia exists, so dose adjustments are necessary when combined with other hypoglycemic agents such as insulin or sulfonylureas, and one should be vigilant for symptoms of hypoglycemia. Caution is advised when driving or operating machinery, and if any adverse reactions are suspected, one should consult healthcare personnel immediately. Finally, the safety and efficacy of this medication have not been established in children, so it is advisable not to use it in those under 18 years of age.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash accompanied by fever, blisters, skin peeling, pain in mucous membranes of mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, jaundice (yellowing of skin or eyes), severe malaise, sudden and severe headache, thunderclap headache, seizures, confusion of consciousness, visual disturbances, paralysis, urination

Mild side effects

• Pharyngitis
• upper respiratory infection
• headache
• constipation
• vomiting
• thirst
• back pain
• dysuria
• polyuria
• nocturia

This medication must be stored in a tightly closed container to prevent exposure to air or moisture. The storage temperature should be maintained between 1 and 30 degrees Celsius.

Appearance

Beige oval film-coated tablet

Package unit

30 tablets (10 tablets/PTP X 3)