Yushidapahjeong 10/100 mg (Dapagliflozin, Sitagliptin)

Adult dosage

Administer 1 tablet of Sitagliptin 100 mg and Dapagliflozin 10 mg once daily regardless of meals. The tablet should be swallowed whole.

This drug contains two components, Sitagliptin and Dapagliflozin, and is primarily used for blood sugar control in patients with type 2 diabetes. The Sitagliptin component can rarely cause serious allergic reactions; therefore, if symptoms such as rash, swelling, or difficulty breathing occur, discontinue use immediately and consult a physician. Moreover, Sitagliptin can induce pancreatic issues such as acute pancreatitis, so careful monitoring is advised if symptoms like abdominal pain, vomiting, or nausea arise. The Dapagliflozin component may cause a reduction in fluid volume and renal function decline, thus patients with poor renal function or at risk of dehydration should have periodic assessments of renal function and blood pressure before and during use. It is not safe to use this drug in patients with type 1 diabetes, diabetic ketoacidosis, or those on dialysis. While on this medication, hypoglycemic symptoms may occur, especially when used in conjunction with other hypoglycemic agents such as insulin or sulfonylureas, increasing the risk of hypoglycemia. This medication may increase the risk of genital and urinary tract infections, so immediate treatment is necessary if symptoms of infection appear, and patients with a history of infections should be more cautious. Women who are pregnant or breastfeeding should avoid using this medication; if pregnancy is confirmed, the medication should be discontinued immediately. Elderly patients or those with impaired renal function may require dosage adjustments and regular monitoring of renal function. In cases of overdose, there is no specific antidote, so symptomatic treatment is recommended, and drug removal via procedures like dialysis may be considered if necessary. Finally, caution is advised while driving or operating machinery during treatment, as hypoglycemic symptoms may occur, and the medication should be kept out of reach of children.

Serious side effects

Hives, severe swelling (angioedema), chest tightness, difficulty breathing, cold sweat, pallor, anaphylaxis, Stevens-Johnson syndrome, acute pancreatitis, hemorrhagic pancreatitis, necrotizing pancreatitis, severe rashes, blisters, skin peeling, pain in oral/ocular mucosa, dyspnea, asthmatic attacks, respiratory distress accompanying cough and fever, jaundice, liver dysfunction symptoms, severe headache, thunderclap headache, seizures, confusion, vision abnormalities, etc.

Mild side effects

• Genital infections
• urinary tract infections
• hypoglycemia
• dizziness
• constipation
• dry mouth
• back pain
• dysuria
• polyuria
• nocturia

This medication is sensitive to air and moisture, so it must be stored in a tightly closed container. When storing, it is important to maintain a room temperature between 1 and 30 degrees Celsius. This will help preserve the medication's effectiveness for a longer period.

Appearance

Biconvex round film-coated tablets colored yellow to orange

Package unit

28 tablets/box [7 tablets (Alu-Alu) x 4]