Januprep Tablet 10/100 mg

Adult dosage

For patients receiving sitagliptin 100 mg and dapagliflozin 10 mg, the dosage is one tablet administered once daily regardless of meals. The tablet should be swallowed whole.

This medication may cause serious allergic reactions within the first 3 months of administration; if symptoms such as skin rash or difficulty breathing occur, discontinue use immediately and consult your physician. While taking this medication, there is a risk of developing pancreatitis, a serious inflammation of the pancreas; if symptoms such as abdominal pain, vomiting, or fever occur, inform healthcare professionals immediately. This medication should not be used in patients with allergies to specific components, type 1 diabetes, diabetic ketoacidosis, or those undergoing dialysis. Particular caution is necessary in patients with impaired kidney function, reduced fluid volume, and the elderly; dosage adjustments and regular monitoring of kidney function should be conducted according to physician's guidance. During treatment, genital infections or urinary tract infections may occur, and active treatment should be sought upon the appearance of signs of infection. This medication may induce hypoglycemia; caution is required when taken with insulin or other hypoglycemic agents, and dosage adjustments may be necessary if hypoglycemic symptoms arise. Symptoms of hypotension or dehydration due to reduced fluid volume may occur; especially in the elderly or those on diuretics, blood pressure and fluid status should be monitored periodically. This medication is not recommended for women who are pregnant or breastfeeding; if pregnancy is confirmed, discontinue use immediately. Safety and efficacy have not been established in children and adolescents under 18 years of age; therefore, use is not advised. In case of overdose, there is no specific antidote; appropriate treatment should be administered according to symptoms, and monitoring in a hospital may be necessary. Care is required when driving or operating machinery, particularly if hypoglycemic symptoms are present; such activities should be avoided.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, anaphylaxis, angioedema, Stevens-Johnson syndrome, severe hypersensitivity reactions, severe rash with high fever, blistering, skin sloughing, mucosal pain in mouth/eyes, acute pancreatitis, fatal/non-fatal hemorrhagic or necrotizing pancreatitis, respiratory issues, shortness of breath or difficulty breathing, asthma attacks, cough with fever accompanied respiratory distress, skin rash

Mild side effects

• Headache
• upper respiratory tract infection
• nasopharyngitis
• diarrhea
• nausea
• constipation
• muscle pain
• limb pain
• back pain
• pruritus

This medication should be stored in a sealed container to protect it from air and moisture. It is recommended to maintain a storage temperature between 1 to 30 degrees Celsius.

Appearance

Beige oval film-coated tablet

Package unit

30 tablets/PTP [(10 tablets/PTP x 3)]