Oliwon Tablet 60 mg (Orlistat)

Adult dose

The recommended dose for adults is 120 mg of orlistat orally 3 times daily, taken with a fat-containing meal or within 1 hour after a meal. Patients should continue a nutritionally balanced, mildly hypocaloric diet in which approximately 30 % of calories are derived from fat. Daily intake of fat, carbohydrate, and protein should be distributed evenly across three meals. This medicine may be omitted if a meal is skipped or contains no fat. Because this medicine may reduce the absorption of some fat-soluble vitamins and beta-carotene, patients are advised to take a multivitamin containing fat-soluble vitamins to ensure adequate nutrition. The vitamin supplement should be taken at least 2 hours before this medicine or at least 2 hours after it, such as at bedtime. Taking more than 120 mg of this medicine 3 times daily does not increase its efficacy. Based on measurements of fecal fat, the effect of this medicine appears 24 ∼ 48 hours after taking the medication. After treatment is discontinued, fecal fat content generally returns to pretreatment levels within 48 ∼ 72 hours. The efficacy and safety of this medicine have not been evaluated for periods exceeding 4 years. Studies have not been conducted in patients with hepatic and/or renal impairment or in older adults.

Child dose

Studies have not been conducted in children under 12 years of age.

This medication should not be used in patients with chronic malabsorption syndrome or biliary obstruction. It should not be taken by individuals allergic to this medication or any of its components. Women who are pregnant or may become pregnant, as well as nursing mothers, should not take this medication. Additionally, this medication contains lactose and should not be administered to patients with lactose intolerance or certain genetic metabolic disorders. Patients with liver damage or symptoms of impaired liver function should use this medication with caution and undergo regular liver function tests. Patients with hyperoxaluria or calcium oxalate kidney stones should also exercise caution. Those allergic to the ingredient Yellow No. 4 should be careful as well. Taking this medication may cause gastrointestinal discomfort, commonly including abdominal bloating, gas, constipation, and fatty stools. Most adverse reactions are mild and temporary, and tend to decrease over time. However, some patients may experience prolonged gastrointestinal symptoms, so if symptoms are severe or persistent, they should consult a doctor. This medication can interfere with the absorption of fat-soluble vitamins such as vitamins A, D, E, and beta-carotene, so supplementation with vitamins is recommended. Vitamin supplements should be taken at least 2 hours before or after taking this medication. If symptoms of impaired liver function, such as loss of appetite, itching, jaundice, changes in urine color, or upper abdominal pain occur while taking this medication, the patient should inform their doctor immediately. Weight loss may affect blood glucose control in diabetic patients, potentially requiring adjustments to their diabetes medications. Excessive weight loss may increase the risk of gallstones, so caution is advised. This medication can interact with other drugs, so individuals taking cyclosporine, anticoagulants, antiepileptics, or antiretrovirals should consult their doctor. Women who are pregnant or nursing should not take this medication, and it has not been established as safe or effective in children under the age of 12. There is insufficient clinical data in elderly patients, so caution is needed when prescribing. In case of overdose, observation for 24 hours is required, and medical personnel should be informed if symptoms occur. This medication should be stored out of reach of children and kept in its original packaging, protected from light and moisture.

• Fatty stools
• abdominal bloating and gas
• increased frequency of stools
• fatty/greasy stools
• greasy bowel movements
• increased bowel movements
• fecal incontinence
• abdominal pain/discomfort
• nausea
• infectious diarrhea

This medication is sensitive to air, light, and moisture, so it must be stored in a tightly sealed container. Additionally, it should be kept in a cool place below 25 degrees Celsius to maintain its efficacy.

Appearance

Yellow oblong film-coated tablets

Package unit

90 tablets/box [10 tablets/PTP x 9], 90 tablets/box [10 tablets/PTP (Alu-Alu) x 9]