Youngjin Da-Dueo Extended-Release Tablet 10/1000 mg

Adult dose

This medication is typically administered once daily with the evening meal. The maximum dosage is 1 daily dose of dapagliflozin 10 mg/extended-release metformin 2000 mg, given as 2 tablets of 5 mg/1000 mg. For patients with no prior experience of diabetes medication treatment and where adequate blood sugar control is difficult with monotherapy, the initial regimen is 1 tablet of 5 mg/500 mg or 10 mg/500 mg once daily. The

This medication is used in diabetes treatment and may cause a rare side effect known as severe lactic acidosis; therefore, caution is needed. It may be risky to use this medication in patients with impaired kidney function, acute illness, or dehydration. Additionally, when taken with other diabetes medications like insulin or sulfonylureas, there may be a risk of hypoglycemia, necessitating dosage adjustments. This medication should not be administered to patients with moderate to severe impairment of kidney function, and should be discontinued during certain periods before and after surgery. Women who are pregnant or breastfeeding should not take this medication, and patients with specific genetic disorders affecting lactose metabolism should also avoid it. During treatment, kidney function and fluid status should be regularly monitored, and immediate consultation with medical personnel is necessary if symptoms of hypotension or dehydration occur. During the use of this medication, genitourinary and urinary tract infections may occur, and timely treatment should be sought if related symptoms arise. Vitamin B12 deficiency may occur, so checking vitamin B12 levels is advisable for prolonged use. Excessive alcohol consumption may increase the risk of side effects from this medication; thus, it should be avoided. Particular caution should be taken when administering this medication to the elderly, regarding the risk of decreased kidney function and fluid loss, and dosage adjustments may be necessary. In case of overdose, seek immediate medical attention for appropriate treatment, and dialysis may be helpful if needed. Lastly, this medication is not recommended for use in children, as safety and efficacy have not been established. Caution should be exercised while driving or operating machinery, as dizziness may occur during the use of this medication.

Serious side effects

• Severe lactic acidosis
• severe hypoglycemia
• acute kidney injury
• lactic acidosis
• severe allergic reactions
• severe edema or urination abnormalities
• ketoacidosis
• urosepsis
• pyelonephritis
• acute cholecystitis

Mild side effects

Hypoglycemia, vulvovaginitis, balanitis and related genital infections, urinary tract infections, fungal infections, reduced fluid volume, thirst, dizziness, constipation, dry mouth, low back pain, dysuria, polyuria, nocturia, vulvar itching, genital itching, increased hematocrit, decreased initial serum creatinine clearance, dyslipidemia, elevated serum creatinine at treatment onset, elevated blood urea, weight loss, headache, paresthesia, tremors, epigastric pain

This medication should be stored in a tightly closed container to protect it from air and moisture, and it is recommended to keep it at room temperature between 1 and 30 degrees Celsius. Proper storage will help maintain the drug's effectiveness and prevent degradation.

Appearance

Yellow, double convex, oval-shaped extended-release film-coated tablet

Package unit

30 tablets/box [(6 tablets/PTP*5)], 30 tablets/bottle