Pimaten Tablet 60/5 mg

Adult dose

The recommended dose for adults is one tablet once daily, taken with water, regardless of meals. It is recommended to take it at the same time every day (e.g., in the morning). Generally, no initial dose adjustment is needed for elderly patients (aged 70 or older). For patients with mild to moderate kidney dysfunction (creatinine clearance 30–80 mL/min), dose adjustment is also not required; however, for severe kidney impairment (creatinine clearance < 30 mL/min), treatment should start with Pimansartan 30 mg. Liver impaired patients do not require dose adjustment if they have mild liver impairment, but patients with moderate to severe liver impairment should not take this medication.

Child dose

The safety and efficacy in pediatric and adolescent patients under 18 years of age have not been established.

This medication can cause serious harm or death to the fetus and newborn if taken during pregnancy, particularly in the second and third trimesters, so it should be discontinued immediately upon confirmation of pregnancy. Patients with allergies to this medication’s active ingredient or similar components, those who are pregnant or breastfeeding, patients on kidney dialysis, those with severely compromised liver function, bile duct obstruction, certain kidney diseases, or diabetic nephropathy should not take this medication. Patients with low blood volume or sodium, impaired kidney function, renal artery hypertension, heart valve disease, severe hypotension, elderly individuals, and those with hypersensitivity to specific pigments should take special caution when using this medication and should be closely monitored. This medication can commonly cause side effects such as dizziness, headaches, facial or limb swelling, urination issues, insomnia, and flushing, while severe side effects such as major renal problems or hypotension may occur rarely. Since this medication lowers blood pressure, patients experiencing symptoms of hypotension should consult a doctor immediately, and in severe cases, seek appropriate treatment at a hospital. This medication can interact with other drugs; therefore, it is essential to inform the doctor if taking potassium-sparing diuretics, lithium, non-steroidal anti-inflammatory drugs, specific antibiotics, and other antihypertensive medications. Taking this medication during pregnancy poses a serious risk to the fetus; thus, women planning a pregnancy or who are pregnant should consult with their doctor before taking it, and it is not recommended during breastfeeding. For children under 18 years old, safety and efficacy have not been established, so it is best not to use it. Generally, elderly patients do not require dose adjustments; however, some elderly individuals may be more sensitive to the medication and should be closely monitored. Patients with moderate to severe liver impairment should not take this medication. In cases of overdose, severe hypotension or cardiac irregularities may occur, requiring immediate medical attention for appropriate treatment. This medication should be kept out of reach of children and should not be transferred to other containers for safety.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in mucous membranes of the mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, abnormal breathing with cough and fever, jaundice (yellowing of skin or eyes), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination problems

Mild side effects

• Dizziness
• orthostatic dizziness
• headaches
• facial swelling
• peripheral edema
• urination difficulties
• insomnia
• flushing
• dyspepsia
• vomiting

This medication is sensitive to light and must be stored in a light-blocking container. Additionally, it is important to store it at room temperature between 1 to 30 degrees Celsius to maintain efficacy.

Appearance

Orange, round-edged, square film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle