Posilogen Es Tablets (Dapagliflozin Propanediol Monohydrate, Sitagliptin Phosphate Monohydrate)

Adult dosage

This medication may be administered at a dosage of 1 tablet once daily with or without food to patients receiving Sitagliptin 100 mg and Dapagliflozin 10 mg. The tablet should be swallowed whole.

This medication may cause severe allergic reactions due to the Sitagliptin ingredient, so if symptoms such as skin rash, breathing difficulty, or swelling of the face or neck occur, discontinue use immediately and consult a healthcare professional. This medication may cause acute pancreatitis, a serious inflammation of the pancreas; therefore, if symptoms such as abdominal pain, nausea, or vomiting develop, inform a healthcare professional immediately. This medication should not be used in patients with type 1 diabetes, diabetic ketoacidosis, or patients undergoing dialysis. In patients with reduced fluid volume or impaired kidney function, this medication may cause low blood pressure or kidney damage, so kidney function and fluid status should be carefully monitored before and during administration. When used in conjunction with medications that have a risk of hypoglycemia, such as insulin or sulfonylureas, this medication may increase the risk of hypoglycemia, so dose adjustment of these medications may be necessary. This medication may increase the risk of genital infections and urinary tract infections, so appropriate treatment should be sought if related symptoms occur. Elderly patients may have a higher risk of reduced fluid volume and low blood pressure, so caution is advised in their use. Women who are pregnant or breastfeeding are advised not to use this medication, and if pregnancy is confirmed, use should be discontinued immediately. Safety and efficacy in pediatric patients under 18 years old have not been established, so use should be avoided in this population. In case of overdose, there is no specific antidote; appropriate management should be implemented based on symptoms, and blood dialysis may be considered if necessary. This medication does not significantly affect the ability to drive or operate machinery, but caution should be exercised as hypoglycemic symptoms may occur. The product should be stored out of reach of children and kept in its original container for safety.

Serious side effects

Urticaria, severe swelling (edema), tightness in the chest, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in mucous membranes of the mouth/eyes, shortness of breath or difficulty breathing, asthma attack, respiratory issues accompanied by cough + fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination

Mild side effects

• Hypoglycemia
• dry mouth
• dizziness
• constipation
• dry mouth
• back pain
• polyuria
• nocturia
• itching of the vulva
• itching of the genitals

This medication should be stored in a tightly sealed container to protect it from air and moisture, and ideally at room temperature between 1 and 30 degrees Celsius. Proper storage will help maintain the effectiveness of the medication for a longer period.

Appearance

Beige oval film-coated tablet

Package unit

30 tablets/box [(10 tablets/PTP x 3)]