Escarb Tablets 60/5 mg

Adult dose

The recommended dosage for this medication is 1 tablet once a day, taken with water regardless of meals. Taking it at the same time each day (e.g., morning) is recommended. No initial dose adjustment is necessary for elderly patients (70 years or younger). No dose adjustment is needed for patients with mild to moderate renal impairment (creatinine clearance 30 to 80 mL/min). For patients with severe renal impairment (creatinine clearance < 30 mL/min), treatment should begin with 30 mg of pimodizide.

Child dose

The safety and efficacy for pediatric and adolescent patients under 18 years have not been established.

This medication can cause serious harm or death to the fetus and newborn if used during pregnancy, especially in the 2nd and 3rd trimesters; therefore, it should be discontinued immediately once pregnancy is confirmed. Patients with allergies to the active ingredient or similar drugs, those who are pregnant or breastfeeding, individuals undergoing dialysis, patients with severe liver disease, those with bile duct obstruction, diabetic patients with certain kidney diseases, individuals with specific genetic lactose intolerance, patients with severe aortic stenosis, patients in shock, etc., should not take this medication. Patients with reduced blood volume or salt, impaired kidney function, renal vascular hypertension, aortic stenosis and mitral valve stenosis, primary aldosteronism, severe hypotension, elderly patients, and those allergic to certain colorants in the medication should use this medicine cautiously. While taking this drug, side effects such as dizziness, headache, facial swelling, urinary disorders, insomnia, flushing may occur, and serious kidney issues or blood pressure drops may also occur in rare cases; any abnormal symptoms should prompt immediate consultation with medical personnel. During use, there may be risks of too low blood pressure or electrolyte imbalances, especially when taken alongside diuretics or with dietary restrictions; hence caution is necessary, and appropriate measures should be taken if symptoms arise. This medication may interact with other antihypertensive agents, potassium-sparing diuretics, lithium, and non-steroidal anti-inflammatory drugs. If taking other medications, be sure to inform your doctor or pharmacist. It should be avoided during pregnancy due to serious risks to the fetus and should be discussed with a professional during breastfeeding since the drug may be passed through breast milk. Safety and efficacy for pediatric patients under 18 years have not been established, and elderly patients may be more sensitive to the medication and require caution during use. In cases of overdose, severe hypotension and heart problems may occur, so seek appropriate medical treatment immediately.

Serious side effects

Acute renal failure, chronic renal failure, acute hepatitis, hepatitis, jaundice, hypotension, syncope, blood pressure drop, severe hypotension, angioedema, urticaria, toxic epidermal necrolysis, heart failure, pulmonary edema, myocardial infarction, arrhythmias (including bradycardia, ventricular tachycardia, atrial fibrillation), pneumonia, lung disease, cough, asthma, hypertension, epilepsy, amyotrophic lateral sclerosis, neuropathy, neuritis, facial paralysis, normal pressure hydrocephalus, spinal stenosis, headache, intracranial hemorrhage

Mild side effects

• Dizziness
• positional dizziness
• headache
• facial swelling
• peripheral edema
• urinary disorders
• insomnia
• flushing
• syncope
• sedation

This medication may be sensitive to light, so it should be stored in a container that protects from light. Additionally, it is best stored at room temperature between 1 to 30 degrees Celsius. This helps maintain the drug's effectiveness and safety.

Appearance

Orange colored, rounded square film-coated tablets

Package unit

30 tablets/bottle, 300 tablets/bottle