Sitagliptin and Dapagliflozin Tablets 10/100 mg (Dapagliflozin Propanediol Monohydrate, Sitagliptin Phosphate Monohydrate)

Adult dosage

This medication can be administered as one tablet once daily for patients receiving 100 mg of sitagliptin and 10 mg of dapagliflozin, regardless of meals. The tablet should be swallowed whole.

This medication can cause allergic reactions, so patients with hypersensitivity should not use it. During treatment, serious pancreatic diseases such as acute pancreatitis may occur, so if symptoms like abdominal pain or vomiting arise, consult a physician immediately. It is contraindicated in patients with type 1 diabetes, diabetic ketoacidosis, and those undergoing dialysis. Patients with impaired renal function or at risk of decreased fluid volume should use this medication with caution, and kidney function and blood pressure should be monitored regularly. As this medication has blood sugar-lowering effects, the risk of hypoglycemia may increase when taken with insulin or sulfonylureas, so dosage adjustments may be necessary. The risk of genital infections or urinary tract infections may increase, so treatment should be sought immediately if infection symptoms occur. Elderly patients or those with liver dysfunction should also use this medication with caution, and regular health status monitoring is recommended. Women who are pregnant or breastfeeding should not take this medication, and if pregnancy is confirmed, use should be discontinued immediately. Symptoms such as decreased fluid volume, hypotension, or ketoacidosis may occur during treatment, and if any abnormal symptoms arise, immediate consultation with healthcare professionals is necessary. In case of overdose, seek medical attention immediately for appropriate treatment, as there is no specific antidote and symptomatic treatment based on the symptoms is necessary. This medication is not recommended for children, as its safety and efficacy have not been established in this population. If driving or operating machinery during treatment, caution is advised due to the risk of hypoglycemia.

Serious side effects

Rash, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, anaphylaxis, angioedema, Stevens-Johnson syndrome, exfoliative skin disease, acute pancreatitis, hemorrhagic pancreatitis, necrotizing pancreatitis, severe rash with high fever, blisters, epidermal peeling, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attacks, cough with fever and respiratory distress, jaundice (yellowing of the skin or eyes).

Mild side effects

• Headache
• upper respiratory infection
• nasopharyngitis
• constipation
• vomiting
• diarrhea
• thirst
• hypoglycemia
• dizziness
• back pain

This medication should be stored in a tightly closed container to prevent exposure to air or moisture, and it is best to keep it at room temperature between 1 and 30 degrees Celsius. Proper storage can help maintain the medication's effectiveness for a longer period.

Appearance

Beige oval film-coated tablets

Package unit

30 tablets/PTP [10 tablets/PTP x 3]