Pimavan ES Tablet 30/2.5 mg (Pimasartan, Amlodipine)

Adult dose

The recommended dose of this medication is 1 tablet once daily, taken with water regardless of meals. It is advised to take it at the same time each day (e.g., in the morning). Patients whose blood pressure is not adequately controlled with Pimasartan 30 mg monotherapy should be administered 30/2.5 mg. Patients whose blood pressure is not adequately controlled with Pimasartan 60 mg monotherapy should be administered 60/2.5 mg.

Child dose

Safety and efficacy for pediatric and adolescent patients under 18 years old have not been established.

This medication can cause serious harm or death to the fetus and newborn if taken during pregnancy, especially in the second and third trimesters, so it should be discontinued immediately upon confirmation of pregnancy. Patients who are allergic to any of the ingredients in this medication, those who are pregnant or breastfeeding, patients undergoing renal dialysis, patients with moderate to severe liver function impairment, individuals with biliary obstruction, specific diabetes patients, and those with genetic conditions such as lactose intolerance should not take this medication. Patients with low blood volume or salt deficiency may experience hypotension when starting this medication or increasing the dose, so their condition should be closely monitored. Caution is also required for patients with impaired kidney function or renovascular hypertension. This medication can cause side effects such as dizziness, headache, facial or peripheral edema, urinary disorders, insomnia, and flushing. Rarely, serious kidney issues, hypotension, liver function anomalies, and other complications have been reported. If symptoms of hypotension occur during treatment, immediate measures, such as lying the patient down and administering fluids if necessary, are required. Regular blood tests are recommended due to the risk of elevated potassium levels. This medication may interact with other antihypertensives, diuretics, potassium-sparing diuretics, certain antibiotics, lithium, grapefruit juice, etc., so it is essential to discuss any medications being taken with a physician or pharmacist. Women who are pregnant or breastfeeding should avoid taking this medication and should consult a healthcare professional if pregnancy is confirmed. Safety and efficacy for children and adolescents under 18 years old have not been established, thus its use is not recommended. Elderly patients may respond more sensitively to this medication, thus caution is advised during use. Patients with moderate to severe liver impairment should not take this medication. In cases of overdose, severe hypotension, palpitations, and bradycardia may occur, and immediate medical attention should be sought if these symptoms arise. This medication should be kept out of reach of children, and transferring it to another container may cause quality deterioration or accidents, so caution is advised.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash associated with high fever, blisters, skin peeling, oral/eye mucosal pain, difficulty or shortness of breath, asthma attacks, respiratory difficulties with cough + fever, yellowing of the skin or eyes (jaundice), extreme malaise, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination

Mild side effects

• Dizziness
• orthostatic dizziness
• headache
• facial edema
• peripheral edema
• urinary disorders
• insomnia
• flushing
• dyspepsia
• vomiting

This medication is sensitive to light and should be stored in a special container that blocks light. Additionally, to maintain the efficacy of the medication, it should be stored at a temperature between 1 to 30 degrees Celsius.

Appearance

White, round, film-coated tablet with a square shape

Package unit

Bottle packaging - 30 tablets/bottle, Bottle packaging - 300 tablets/bottle