Pimadipine Tablet 60/2.5 mg (Pimasartan Potassium, Amlodipine)

Adult dose

The recommended dose of this medication is 1 tablet once daily, to be taken with water regardless of meal timing. It is recommended to take it at the same time every day (e.g., in the morning). If blood pressure remains uncontrolled, it may be possible to adjust the dose with Pimasartan monotherapy before switching to this medication. In patients with renal impairment, treatment should start with Pimasartan 30 mg in the case of severe renal impairment. In patients with hepatic impairment, the drug should not be administered in cases of moderate or severe liver impairment.

This medication can cause serious harm to the fetus and newborn if taken during the second and third trimesters of pregnancy, so it should be discontinued immediately upon confirmation of pregnancy. People with allergies to this medication or similar class medications, pregnant or breastfeeding individuals, patients undergoing kidney dialysis, patients with severe liver impairment, patients with biliary obstruction, diabetic patients with certain kidney diseases, and patients with specific genetic metabolic disorders should not take this medication. Patients with low blood volume or sodium deficiency, patients with impaired kidney function, patients with renovascular hypertension, patients with aortic or heart valve diseases, patients with severe hypotension, and elderly individuals should take this medication with special caution. Side effects such as dizziness, headache, facial or limb swelling, urinary disorders, insomnia, and flushing may occur when taking this medication, so it is important to consult healthcare professionals if these symptoms arise. Low blood pressure may occur at the beginning of treatment, so especially patients on diuretics or those with decreased blood volume should be closely monitored. This medication may interact with other drugs, so it is essential to inform healthcare professionals of any current medications, especially when taken in combination with potassium supplements, diuretics, lithium, and non-steroidal anti-inflammatory drugs. During pregnancy, it should be avoided as it may pose risks to the fetus, and during breastfeeding, it is recommended to either stop breastfeeding or discontinue medication as the drug may pass into breast milk. The safety and efficacy in children under 18 years old have not been established, so it is advisable to avoid use in this age group. In case of overdose, symptoms such as hypotension, arrhythmias, and shock may occur, requiring immediate emergency treatment, and appropriate measures should be taken following healthcare professional instructions. This medication should be stored out of reach of children and not transferred to other containers for safety, and caution should be exercised when driving or operating hazardous machinery while taking the medication.

Serious side effects

Urticaria, facial swelling, angioedema, toxic epidermal necrolysis, jaundice, acute renal failure, chronic renal failure, acute hepatitis, acute pancreatitis, hemorrhagic duodenal ulcer, intracranial hemorrhage, transient ischemic attack, atherosclerosis, exacerbation of cerebral infarction, cerebral hemorrhage, pulmonary embolism, pneumonia, pulmonary disease, atrial fibrillation, bradycardia, ventricular arrhythmia, heart failure, death, myocardial infarction, arrhythmia, shock, difficulty breathing, asthma, respiratory distress accompanied by cough and fever, severe swelling (edema)

Mild side effects

Dizziness, headache, orthostatic dizziness, insomnia, flushing, urinary disorders, facial swelling, peripheral edema, dyspepsia, vomiting, nausea, abdominal pain, weakness, foreign body sensation, elevated liver enzyme levels, reduced platelet count, increased serum creatine phosphokinase levels, cough, muscle spasms, musculoskeletal stiffness, itching, localized urticaria, erectile dysfunction, syncope, sedation, migraine, pruritus, rash, angioedema, erythema multiforme, palpitations, drowsiness.

Store this medication in a tightly sealed container that blocks light and prevents air infiltration. It is recommended to maintain a storage temperature between 1 to 30 degrees Celsius.

Appearance

Yellow, round, square-shaped film-coated tablet

Package unit

Bottle packaging - 30 tablets/bottle, Bottle packaging - 300 tablets/bottle