Viewing nowCombinationCarolnight Soft Capsule
Ibuprofen 200mg · Diphenhydramine Hydrochloride 25mg
Soft capsule · OTC medication · Combination
Ildong Pharmaceutical Co., Ltd.

MFDS item code 202204634 · Notified 2022.12.26
Relief of acute nighttime pain (pain, insomnia)
This medication is used to alleviate temporary insomnia caused by pain, especially acute pain that worsens at night.
For difficulty sleeping due to pain, take 1-2 capsules once a day before bedtime. Ensure not to exceed 1,200mg of ibuprofen and 75mg of diphenhydramine within 24 hours, including this medication. The dosing interval should be more than 4 hours after taking ibuprofen and/or diphenhydramine. If the cause of symptoms is undetermined, do not take continuously for more than 5 days.
This medication may cause gastric bleeding in individuals who regularly consume more than three alcoholic beverages a day, so consultation with a doctor or pharmacist is mandatory. Individuals with cardiovascular diseases or risk factors, as well as those taking this medication for a long period, have a higher risk of cardiovascular issues such as myocardial infarction or stroke. This medication can cause serious gastrointestinal adverse reactions such as gastric bleeding, ulcers, and perforation, especially in the elderly or those taking it long-term. Individuals with allergies to the ingredients of this medication or a history of gastrointestinal ulcers, bleeding, asthma, severe liver and kidney dysfunction, heart failure, hypertension, glaucoma, epilepsy, and specific diseases should not take it. Pregnant or breastfeeding women are advised not to take this medication, and women who may become pregnant should also exercise caution. While taking this medication, avoid using it in combination with drugs such as ACE inhibitors, lithium, certain diuretics, methotrexate, anticoagulants, and selective serotonin reuptake inhibitors (SSRIs). Additionally, do not take it with other non-steroidal anti-inflammatory drugs, do not exceed the recommended dose, and avoid alcohol. Since drowsiness or dizziness may occur during use, caution is required when driving or operating machinery. Before taking this medication, consult a doctor or pharmacist if you have a history of blood abnormalities, liver and kidney dysfunction, heart disease, hypertension, or hypersensitivity. If severe allergic reactions, gastric bleeding, skin rashes, liver dysfunction, breathing difficulties, visual disturbances, or kidney dysfunction occur during use, discontinue and consult healthcare professionals immediately. Do not take it long-term, administer it to children under parental supervision, and store it in a cool, dry place away from direct sunlight. It is also important to keep it out of reach of children.
Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with high fever, blisters, peeling skin, pain in mucous membranes of mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, respiratory issues accompanied by cough + fever, yellowing of skin or eyes (jaundice), extreme lethargy, sudden and severe headaches, thunderclap headaches, seizures, confusion, visual disturbances, paralysis, urination changes
Not everyone experiences these, and they can vary from person to person.
This medication should not be taken with ACE inhibitors, lithium, furosemide and thiazide diuretics, methotrexate, coumarin anticoagulants (such as warfarin), selective serotonin reuptake inhibitors, other hypnotics, sedatives, MAO inhibitors (including antidepressants, antipsychotics, mood stabilizers, and anti-Parkinson's drugs), cold medications, antipyretic analgesics (such as aspirin, acetaminophen, naproxen), cough suppressants, expectorants, and oral medications containing antihistamines.
Avoid alcohol while taking this medication.
This medication may be sensitive to air or moisture, so it is important to store it in a tightly sealed container. The storage temperature should be maintained at room temperature between 1 and 30 degrees Celsius, avoiding extremely hot or cold places.
Transparent oval soft capsule containing a colorless or pale yellow transparent content
10 capsules/PTP
Even with the same ingredient, strength, dosage form and how it is taken can differ.
Viewing nowCombinationIbuprofen 200mg · Diphenhydramine Hydrochloride 25mg
Soft capsule · OTC medication · Combination
Ildong Pharmaceutical Co., Ltd.
CombinationIbuprofen 200mg · Diphenhydramine Hydrochloride 25mg
Soft capsule · OTC medication · Combination
RP Bio Co., Ltd.
CombinationIbuprofen 200mg · Diphenhydramine Hydrochloride 25mg
Soft capsule · OTC medication · Combination
Daewoong Pharmaceutical Co., Ltd.
CombinationIbuprofen 200mg · Diphenhydramine Hydrochloride 25mg
Soft capsule · OTC medication · Combination
Joah Pharmaceutical Co., Ltd.
Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.
QIf I feel drowsy the morning after taking it, is it safe to drive?
Answers 1 · 2026.09.14
QIs this medication taken when I have back pain and cannot sleep?
Answers 1 · 2026.09.14
For anything that needs medical judgment, consult a doctor or pharmacist.
This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.