Sitafol M Tablets 50/1000 mg

Adult dose

This medication is typically taken twice daily with food, and the dosage is gradually increased to reduce gastrointestinal side effects associated with metformin. 1. For patients not currently treated with metformin: Start with 50/500 mg of this medication, taking 1 tablet twice daily, and it can be increased to 50/1000 mg, 1 tablet twice daily. 2. For patients receiving treatment with metformin.

This medication consists of two main ingredients, each used in the treatment of diabetes. The first ingredient is a drug that helps control blood sugar, while the second ingredient promotes insulin secretion. When taking this medication, allergic reactions may occur; therefore, if any symptoms such as skin rash, hives, difficulty breathing, or swelling of the face or neck appear, discontinue use immediately and consult a physician. Additionally, this medication can lead to a serious pancreatic condition called pancreatitis; hence, if symptoms such as abdominal pain, vomiting, or loss of appetite occur during treatment, inform your healthcare provider immediately. Patients with moderate to severe renal impairment, or those with acute conditions such as severe infections, dehydration, or acute myocardial infarction should not take this medication, and it should be discontinued before and after surgery or examinations utilizing radioactive iodine contrast agents. This medication is not to be administered to pregnant or breastfeeding women or children under the age of 18. Patients taking this medication should be aware of symptoms of hypoglycemia, particularly when used in conjunction with other hypoglycemic agents or insulin, as the risk of hypoglycemia may increase. Symptoms of hypoglycemia include dizziness, tremors, cold sweat, and confusion, and appropriate measures should be taken immediately if such symptoms occur. Alcohol consumption can increase the risk of lactic acidosis, a side effect of this medication; thus, excessive drinking should be avoided during treatment. Patients using this medication should regularly monitor their renal function and undergo blood tests to check their health status, and it is also recommended to periodically check vitamin B12 levels. Furthermore, if symptoms such as severe joint pain or blistering skin occur while taking this medication, consult a physician immediately. Drug interactions may also occur, so inform your doctor or pharmacist if you are taking other medications, as dose adjustments may be necessary for certain combinations. Finally, in case of an overdose of this medication, seek immediate medical attention to receive appropriate care, as some components can be removed by hemodialysis.

Serious side effects

Hives, angioedema, anaphylaxis, exfoliative skin conditions including Stevens-Johnson syndrome, acute pancreatitis (including hemorrhagic or necrotizing), acute renal failure, shortness of breath, unstable angina, acute renal failure, lactic acidosis, severe hypoglycemia, severe joint pain, blistering dermatitis similar to pemphigus, elevated liver enzymes, liver disorders (jaundice), elevated blood pressure and severe edema, severe allergic reactions, severe skin adverse reactions, respiratory issues.

Mild side effects

• Diarrhea
• upper respiratory tract infection
• headache
• nausea
• vomiting
• abdominal pain
• nasopharyngitis
• constipation
• muscle pain
• limb pain

This medication should be stored in a tightly closed container to prevent exposure to air or moisture, and it is advisable to keep it at room temperature between 1 to 30 degrees Celsius. Proper storage maintains the efficacy of the medication.

Appearance

Dark red oval film-coated tablet

Package unit

56 tablets/box [(14 tablets/PTP x 4)], 200 tablets/bottle, 30 tablets/bottle