Exmet 50/850 mg

Adult dose

This medication is typically taken twice a day with food and the dosage is gradually increased to minimize gastrointestinal side effects caused by metformin. 1. For patients not currently being treated with metformin: The initial dose of this drug 50/500 mg is 1 tablet twice daily, and can be increased to 1 tablet twice daily of 50/1000 mg. 2. For patients currently receiving metformin treatments:

This medication contains two components, sitagliptin and metformin, primarily used for blood sugar control in Type 2 diabetes patients. During the usage of this medication, severe allergic reactions may occur; if symptoms such as skin rash, hives, or difficulty breathing develop, discontinue use immediately and consult a doctor. There is a risk of acute pancreatitis, so if symptoms such as abdominal pain, nausea, or vomiting occur, notify healthcare personnel right away. Severe side effects like hypoglycemia or lactic acidosis may arise, thus this medication should not be used, especially by patients with impaired kidney function or liver dysfunction. In cases of poor kidney function or acute illness, or around the time of surgery, the use of this medication should be temporarily halted and may be reinitiated only after kidney function recovers to normal. This medication is not recommended for use during pregnancy or breastfeeding, and its safety and efficacy in pediatric patients under 18 years of age have not been established. Regular blood sugar and kidney function tests are necessary during treatment, and since vitamin B12 deficiency may occur, regular blood tests are advised. Excessive alcohol consumption can increase the risk of lactic acidosis; hence, avoiding alcohol is advisable. When used in conjunction with other hypoglycemic agents, particularly insulin or sulfonylurea medications, the risk of hypoglycemia may increase, necessitating dose adjustment. If severe joint pain or skin blistering occurs during medication, consult a physician immediately, and medication may need to be discontinued. It is important to consistently maintain diet and exercise therapy while taking this medication and to regularly consult healthcare professionals to monitor treatment effects and side effects.

Serious side effects

Hives, severe swelling (angioedema), anaphylaxis, rash, exfoliative skin diseases (including Stevens-Johnson syndrome), severe allergic reaction, acute pancreatitis (including hemorrhagic or necrotizing types), acute kidney failure, difficulty breathing, severe hypoglycemia, severe joint pain with disability, blistering dermatitis, liver abnormalities (increased liver enzymes, risk of jaundice), lactic acidosis, serious neurological symptoms (headache, confusion, etc.), hypertension

Mild side effects

• Diarrhea
• upper respiratory tract infection
• headache
• nausea
• vomiting
• abdominal pain
• nasopharyngitis
• constipation
• myalgia
• limb pain

This medication should be stored in a tightly sealed container to prevent air exposure, and it is advisable to keep it at room temperature between 1°C and 30°C. This helps to maintain the drug's efficacy and prevent degradation.

Appearance

Dark pink oval film-coated tablet

Package unit

56 tablets/box [14 tablets/PTP×4], 30 tablets/bottle, 200 tablets/bottle