Janumet Tablet 50/1000 mg

Adult dose

This medication is generally taken twice daily with food, and to reduce gastrointestinal side effects associated with metformin, the dosage should be increased gradually. The initial dose is determined based on the patient's current treatment regimen. 1. Patients not currently treated with metformin: Take this medication at 50/500 mg twice daily, with an option to increase to 50/1000 mg. 2. Patients on metformin

This medication contains sitagliptin and metformin, and is used in diabetes treatment. While taking this medication, serious allergic reactions may occur; therefore, if symptoms such as rashes, hives, or difficulty in breathing appear, stop taking the medication immediately and consult a doctor. Acute pancreatitis may occur, so inform healthcare providers immediately if severe abdominal pain or vomiting occurs. Patients with severely impaired kidney function or at risk for acute renal failure should not take this medication and should regularly have their kidney function tested. Avoid taking this medication if you have severe infections, dehydration, heart disease, heart failure, or acute myocardial infarction. When undergoing tests with iodinated contrast media, this medication should be temporarily discontinued and should only be resumed after confirming normal kidney function post-exam. Pregnant or potentially pregnant women, as well as breastfeeding women, should not take this medication. This medication may cause hypoglycemia, so particular caution is needed when skipping meals, eating irregularly, exercising vigorously, or taking it with other hypoglycemic agents. Gastrointestinal disturbances, diarrhea, nausea, vomiting, headache, etc., may occur and should be discussed with a doctor if severe. Alcohol may increase the risk of side effects with this medication, so alcoholic beverages should be avoided while taking it. In cases where surgery is planned, the medication should be stopped 48 hours prior, and should only be resumed after verifying normal kidney function post-surgery. Elderly patients may have an increased risk of kidney function decrease; thus, dosage adjustments and regular kidney function tests are needed. During the course of treatment, regular checks of blood glucose, kidney function, and blood tests should be conducted to monitor for abnormalities. In case of overdose, visit a medical institution immediately for appropriate treatment, and blood dialysis may be necessary.

Serious side effects

Hives, severe hypersensitivity reactions (anaphylaxis, angioedema, Stevens-Johnson syndrome, etc.), severe swelling (edema), chest tightness, difficulty in breathing, cold sweat, pallor, severe rash accompanied by high fever, blisters, skin peeling, pain in the mucous membranes of the mouth/eyes, shortness of breath or difficulty in breathing, asthma attacks, respiratory issues accompanied by coughing and fever, yellowing of the skin or eyes (jaundice), profound lethargy

Mild side effects

• Diarrhea
• nausea
• vomiting
• abdominal pain
• upper respiratory tract infection
• nasopharyngitis
• headache
• hypoglycemia
• constipation
• lethargy

This medication should be stored in a tightly closed container to prevent air or moisture exposure, and is safe to store at room temperature between 1 and 30 degrees Celsius. Therefore, avoid direct sunlight and do not leave it in excessively hot or cold places.

Appearance

Oval tablet with a dark red film coating

Package unit

56 tablets/box [14 tablets/PTP×4], 30 tablets/bottle, 200 tablets/bottle