Medication info

Parafen Soft Capsule (Clonixin Lysine Salt)

OTC medicationSoft capsuleOral
Ingredient · strength
Clonixin Lysinate›125mg / 1 capsule
Manufacturer / importer
Kyungnam Pharmaceutical Co., Ltd.
Appearance
Blue transparent oval soft capsule containing a pale yellow transparent liquid
Packaging
10 capsules/PTP, 12 capsules/PTP
Approval status
Active

MFDS item code 202204179 · Notified 2022.11.21

Summary

Main use
Relief of mild to moderate pain (headache, toothache, muscle pain, etc.)
Who takes it
Adults
Adult dose
Adults: Administer 125∼250 mg per dose orally 3 times daily as clonixin lysinate.

Ingredients

Manufacturer
Kyungnam Pharmaceutical Co., Ltd.

Efficacy & effects

Relief of mild to moderate pain (headache, toothache, muscle pain, etc.)

  • Muscle pain
  • neuralgia
  • pain after trauma
  • postoperative pain
  • headache
  • toothache
  • earache
View approved original text

This medication is used to relieve various mild or moderate pains such as muscle pain, neuralgia, pain after trauma and surgery, headache, toothache, and earache.

How to take

Adult dose

Adults: Administer 125∼250 mg per dose orally 3 times daily as clonixin lysinate.

Precautions

This medication can cause gastrointestinal bleeding if taken regularly by individuals who consume more than three drinks a day, so consultation with a doctor or pharmacist is essential. It may also increase the risk of cardiovascular diseases, so individuals with a history of heart disease or stroke, or those with risk factors should be especially cautious, and if cardiovascular symptoms appear during treatment, prompt consultation with medical personnel is necessary. Additionally, this medication can cause serious gastrointestinal side effects such as gastrointestinal bleeding, ulcers, or perforations, and particularly elderly individuals or those with a history of gastrointestinal disorders should be more careful. Patients with a history of peptic ulcers, those who have previously experienced gastrointestinal issues due to medications, individuals allergic to this drug or its ingredients, people who have had allergic reactions to aspirin or other nonsteroidal anti-inflammatory drugs, pregnant women or women who may become pregnant, individuals with severe liver, kidney, or heart diseases, and those with inflammatory bowel diseases should not take this medication. While using this medication, it is recommended not to take other nonsteroidal anti-inflammatory drugs, ACE inhibitors, angiotensin II receptor antagonists, aspirin, diuretics, lithium, methotrexate, anticoagulants, cyclosporine, tacrolimus, antiplatelet agents, selective serotonin reuptake inhibitors, corticosteroids, and to consult medical personnel if such combinations are necessary. Those with a history of peptic ulcers or elderly individuals, and patients with high blood pressure, heart failure, asthma, liver dysfunction, or kidney dysfunction should definitely consult with a doctor or pharmacist before taking this medication. It is advisable to avoid breastfeeding while using this medication, and to immediately stop taking it and consult medical personnel if any unusual symptoms such as nausea, vomiting, abdominal pain, skin rash, anemia, impaired liver function, drowsiness, or headache appear. Dosage should be minimized in duration and amount, accompanied by regular blood tests and liver and kidney function tests to monitor for adverse reactions. This medication serves as symptomatic treatment to relieve inflammation and pain, and should not replace causal treatment; proper antibiotics should be used in conjunction for infectious inflammation. Individuals with a history of gastrointestinal bleeding or ulcers, patients with high blood pressure, heart failure, or impaired kidney or liver function should pay particular attention when taking this medication and consult healthcare professionals immediately if any adverse symptoms occur. Moreover, this medication can cause serious allergic reactions on the skin; hence, it should be immediately discontinued if rash or itching occurs. Lastly, it should be stored out of children's reach and not transferred to other containers.

Side effects

Gastrointestinal bleeding, serious cardiovascular thrombotic reaction, myocardial infarction, stroke, bleeding of the stomach or intestines, ulcers, perforation, nausea, vomiting, diarrhea, constipation, abdominal pain, peptic ulcer, shock, rash, itching, anemia, elevated AST, elevated ALT, drowsiness, headache, dizziness, cold sweat, chills, abnormal euphoria, jaundice, fulminant hepatitis, liver necrosis, liver failure, anemia, skin rash, exfoliative dermatitis, mucous membrane syndrome, toxic epidermal necrolysis, severe bronchospasm

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to protect it from air or moisture. Maintaining a storage temperature between 1 degree and 30 degrees Celsius is essential to preserve the effectiveness and safety of the medication.

Appearance and packaging

Appearance

Blue transparent oval soft capsule containing a pale yellow transparent liquid

Package unit

10 capsules/PTP, 12 capsules/PTP

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.