Dapaone M Extended Release Tablet 5/500 mg

Adult dose

This medication is typically administered once daily with the evening meal. The maximum dosage is once daily dapagliflozin 10mg / extended-release metformin 2000mg, given as 2 tablets of 5mg/1000mg. If there is no prior experience with diabetes medication treatment, the initial regimen is one tablet of 5mg/500mg or 10mg/500mg once daily. To reduce metformin-related gastrointestinal side effects, the dosage should be adjusted gradually.

This medication assists in controlling blood sugar levels. However, it may rarely cause a serious side effect called lactic acidosis, which results from excessive lactate accumulation in the blood, so caution is needed. Additionally, when used with insulin or sulfonylurea medications, there is a risk of hypoglycemia, thus extreme care is necessary. This medication should not be administered to certain patients. For example, patients with allergies to this drug or severely impaired kidney function, those in a dehydrated state, or patients with severe infections, heart issues, or acute myocardial infarction should not take this medication. Women who are pregnant or breastfeeding, as well as patients with genetic lactose intolerance, should also avoid using this drug. Caution is required when this medication is administered to patients with mildly impaired kidney function or dehydration. Particularly, elderly patients or those on diuretics may experience blood pressure drops or worsening kidney function, thus their condition should be closely monitored before and after administration. During the use of this medication, genital infections or urinary tract infections may occur, which are more common in females. Various side effects such as dizziness, constipation, dry mouth, and lower back pain have also been reported, so consultation with healthcare professionals is necessary if symptoms occur. This medication is not recommended for patients with impaired liver function, and alcohol intake should be avoided as it may increase the risk of lactic acidosis. Also, it should be temporarily discontinued around certain examinations or surgeries involving radiological contrast agents, and it should only be resumed after confirming normal kidney function. This drug may interact with other medications, so if currently taking any, it is critical to inform healthcare providers. When used with diuretics, antihypertensive medications, insulin, or insulin secretagogues, the risk of hypoglycemia or hypotension may increase. Pregnant women or women who may become pregnant, as well as breastfeeding women, should not use this medication, and its safety in children has not yet been established. In case of overdose, appropriate treatment is necessary, and this medication should be kept out of the reach of children. Finally, during the use of this medication, dizziness may occur, necessitating caution while driving or operating machinery.

Serious side effects

• Lactic acidosis
• severe hypoglycemia
• acute kidney injury
• renal impairment
• diabetic ketoacidosis
• urosepsis
• pyelonephritis
• severe allergic reactions
• severe edema
• liver abnormality (jaundice)

Mild side effects

• Hypoglycemia
• vulvovaginal infection
• balanitis and related genital infections
• urinary tract infections
• fungal infections
• dizziness
• constipation
• dry mouth
• lower back pain
• urinary pain

This medication may be sensitive to air and moisture, so it should be stored in a tightly sealed container. It is best to maintain a storage temperature between 1 to 30 degrees Celsius to preserve the medication's effectiveness for a longer period.

Appearance

Orange-colored, biconvex, oval-shaped film-coated tablet

Package unit

30 tablets/bottle