Damec Extended-Release Tablet 5/500 Milligrams

Adult dose

This medication is generally administered once daily in conjunction with the evening meal. The maximum dosage is dapagliflozin 10mg/extended-release metformin 2000mg once daily, given as 2 tablets of 5mg/1000mg. When used as initial therapy, the recommended starting dosage is one tablet of 5mg/500mg or 10mg/500mg once daily. The dosage should be adjusted gradually to reduce gastrointestinal side effects of metformin. Metformin

This medication is used for diabetes treatment, and one of its active ingredients, metformin hydrochloride, can rarely cause a serious side effect known as lactic acidosis. Lactic acidosis is a dangerous condition that occurs when lactic acid builds up in the body, with symptoms that may include weakness, muscle pain, shortness of breath, fatigue, and abdominal pain. Caution is needed as the risk of hypoglycemia may increase when this medication is used in combination with insulin or sulfonylureas. If hypoglycemic symptoms occur, immediate consultation with medical personnel is necessary. This medication should not be used in patients with moderate or severe renal impairment, dehydration, severe infections, cardiac dysfunction, or acute diseases such as acute myocardial infarction. Additionally, it should be avoided by pregnant or nursing women. Patients with decreased fluid volume or low blood pressure, the elderly, and those with impaired kidney function should regularly monitor their kidney function and blood pressure status when using this medication, and dosage adjustments may be necessary. This medication may increase the risk of genital infections or urinary tract infections, so if symptoms of infection occur, immediate treatment is required. Furthermore, while taking this medication, vitamin B12 levels may decrease, so it is advisable to check vitamin B12 levels during prolonged use. Before undergoing surgery or iodine contrast examinations, this medication should be temporarily discontinued and resumed only after confirming normal kidney function. Excessive alcohol consumption may increase the risk of side effects when taken with this medication, so it should be avoided. This medication does not significantly affect driving or operating machinery, but caution should be exercised as dizziness may occur. Finally, this medication should be kept out of the reach of children and stored in its original container to maintain quality.

Serious side effects

Lactic acidosis, severe hypoglycemia, urosepsis and pyelonephritis, acute kidney injury and renal dysfunction, severe allergic reactions, severe swelling or urination abnormalities, severe skin reactions, sudden and very severe headaches, Guillain-Barré syndrome, atrial fibrillation, acute cholecystitis, ketosis, necrotizing fasciitis

Mild side effects

• Vulvitis
• balanitis and related genital infections
• urinary tract infections
• fungal infections
• hypoglycemia
• decreased fluid volume
• dry mouth
• dizziness
• constipation
• dry mouth

This medication may be sensitive to air and moisture, so it must be stored in a tightly sealed container. The recommended storage temperature is room temperature between 1 and 30 degrees Celsius. Proper storage will help maintain the effectiveness and safety of the medication over time.

Appearance

Orange, biconvex, egg-shaped film-coated tablet

Package unit

30 tablets/bottle