Posimet Extended-release Tablet 5/500 mg

Adult dose

This medication is generally administered once daily with the evening meal. The maximum dose is dapagliflozin 10 mg/metformin extended-release 2000 mg once daily, with 2 tablets of 5 mg/1000 mg. When used as initial therapy, the recommended starting dose is 1 tablet of 5 mg/500 mg or 10 mg/500 mg once daily. To reduce gastrointestinal side effects of metformin, the dosage should be adjusted gradually.

This medication is used for the treatment of diabetes and should not be used in patients with poor kidney function or certain health conditions. This medication can rarely cause a serious condition called lactic acidosis, and medical consultation should be sought immediately if symptoms appear. Care should be taken as hypoglycemic symptoms may occur if taken with insulin or other diabetes medications. Patients with impaired kidney function or dehydration must undergo evaluation by a doctor before taking this medication, and kidney function and fluid status should be regularly monitored during treatment. This medication may increase the risk of genital and urinary tract infections, so any symptoms of infection should be treated immediately. Women who are pregnant or breastfeeding should not use this medication, and if pregnant or planning pregnancy, should discontinue use immediately. Elderly patients have a higher risk of decreased kidney function and reduced fluid volume; therefore, dosage adjustment and careful monitoring are required. This medication may interact with certain drugs, so it is essential to inform healthcare professionals of any other medications being taken. In the case of overdose, immediate medical attention should be sought, and this medication should be stored out of the reach of children.

Serious side effects

Severe lactic acidosis, severe hypoglycemia, rash, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, oral/ocular mucosal pain, shortness of breath or difficulty breathing, asthma attack, respiratory distress accompanied by cough and fever, yellowing of the skin or eyes (jaundice), extreme fatigue, sudden and severe

Mild side effects

Vulvovaginitis, balanitis and related genital infections, urinary tract infections, hypoglycemia (when combined with insulin or sulfonylureas), dry mouth, dizziness, constipation, back pain, polyuria, nocturia, vulvar itching, genital itching, increased hematocrit, initial decrease in creatinine clearance, dyslipidemia, initial increase in serum creatinine, elevated blood urea, weight loss, headaches, paresthesia, tremors,

This medication should be stored in a sealed container to prevent exposure to air or moisture and should be kept at a temperature between 1 and 30 degrees Celsius. Proper storage will maintain the effectiveness and safety of the medication.

Appearance

Orange, bilaterally convex, egg-shaped film-coated tablet

Package unit

30 tablets/bottle