K-Duo Sustained-release Tablets 10/500 mg

Adult dose

This medication is generally administered once daily with the evening meal. The maximum dosage is one daily dose of dapagliflozin 10 mg/sustained-release metformin 2000 mg, administered as 2 tablets of 5 mg/1000 mg. The recommended starting dose when used as initial therapy is one tablet of 5 mg/500 mg or 10 mg/500 mg taken once daily. This medication should be swallowed whole and should not be crushed, cut, or chewed.

This medication is used for the treatment of diabetes and should not be used in patients with decreased kidney function, serious infections, dehydration, acute myocardial infarction, or other such conditions. During the course of treatment, there is a rare but serious risk of lactic acidosis, so if symptoms such as difficulty breathing, muscle pain, or fatigue occur, contact a doctor immediately. The risk of hypoglycemia may be present when used in conjunction with insulin or other diabetic medications; therefore, blood sugar levels should be monitored regularly, and medication dosages adjusted if necessary. Women who are pregnant or breastfeeding should not use this medication, and it should be discontinued immediately if pregnancy is confirmed. Elderly patients with decreased kidney function or reduced fluid volume should use this medication with caution, and regular kidney function tests and fluid status checks are recommended. It is advisable to avoid alcohol while using this medication, and gastrointestinal disturbances or infection symptoms may occur; thus, informing healthcare personnel of any onset of symptoms is important. Additionally, this medication contains certain dyes, so use with caution if allergic to any of these ingredients, and exercise caution while driving or operating machinery during treatment. In case of overdose, seek medical attention immediately and keep the medication in its original container out of reach of children.

Serious side effects

Lactic acidosis, severe hypoglycemia, Guillain-Barré syndrome, bacterial pneumonia, sialadenitis, acute cholecystitis, ketoacidosis, urosepsis, pyelonephritis, acute kidney injury, renal impairment, severe rash with fever, blisters, skin peeling, oral/ocular mucosal pain, severe swelling, elevated blood pressure, severe allergic reactions, hives, significant swelling, chest tightness, difficulty breathing, cold sweats, pallor, shortness of breath or difficulty breathing, asthma

Mild side effects

• Vulvovaginitis
• balanitis and related genital infections
• urinary tract infections
• hypoglycemia
• reduced fluid volume
• thirst
• dizziness
• constipation
• dry mouth
• low back pain

This medication may be sensitive to air or moisture, so it should be stored in a sealed container. It is best to maintain a storage temperature between 1 and 30 degrees Celsius at room temperature to preserve the drug's effectiveness.

Appearance

Pink, oval-shaped, double-coated film tablets

Package unit

30 tablets/bottle