Medication info

Sepiderm G Cream

OTC medicationCream
Ingredient · strength
Betamethasone Valerate›0.61mg / 1gGentamicin Sulfate›1mg / 1g
Manufacturer / importer
지엘파마(주)
Appearance
White creamy preparation
Packaging
30 grams / tube
Approval status
Active

MFDS item code 202203646 · Notified 2022.09.23

Summary

Main use
Treatment of allergic and inflammatory skin diseases (eczema, atopic dermatitis, etc.) and first-degree burns
Who uses it
Adults
Adult dosage
Apply an appropriate amount to the affected area 1 to 3 times a day.

Ingredients

Manufacturer
지엘파마(주)

Efficacy & effects

Treatment of allergic and inflammatory skin diseases (eczema, atopic dermatitis, etc.) and first-degree burns

  • Allergic skin diseases
  • inflammatory skin diseases
  • eczema
  • contact dermatitis
  • seborrheic dermatitis
  • atopic dermatitis
  • photodermatitis
  • chronic simple eczema
  • scabies
  • exfoliative dermatitis
  • itching
  • psoriasis
View approved original text

This medication is used for allergic or inflammatory skin diseases such as eczema, contact dermatitis, seborrheic dermatitis, atopic dermatitis, and for first-degree burns with secondary infection. It effectively alleviates inflammation and itching caused by these skin conditions to improve symptoms.

Dosage and Administration

Adult dosage

Apply an appropriate amount to the affected area 1 to 3 times a day.

Precautions

This medication should not be used in patients with skin infections, especially those with bacterial, fungal, viral, or parasitic skin infections, as it may worsen the condition. People with a history of allergy or hypersensitivity to the ingredients in this medication should not use it. Patients with eczematous external otitis who have a perforated tympanic membrane should be cautious as its use may delay healing. Patients with skin ulcers or severe burns or frostbite should also avoid using this medication as it may delay skin regeneration. This medication is not suitable for patients with perioral dermatitis, common acne, or rosacea. Patients allergic to aminoglycoside antibiotics or bacitracin should not use this medication. Patients with a history of allergy to propylene glycol should be very cautious when using this medication. Pregnant or potentially pregnant women, nursing mothers, and children should consult a doctor or pharmacist before using this medication. If symptoms of skin infection, irritation, itching, rash, erythema, or skin dryness occur, stop using the medication immediately and consult a specialist. Long-term use may lead to skin thinning, vasodilation, pigment changes, and other side effects, so if symptoms appear, reduce the dosage or switch to another medication. Using this medication extensively or under occlusive dressings for long periods may have systemic effects, so caution is advised, and regular monitoring may be required. Extra care is needed when applying around the eyes due to the risk of increased intraocular pressure or glaucoma. Patients with impaired kidney function or hearing loss are advised not to use this medication for long periods. It is essential to adhere to the prescribed dosage and usage. When applying to children, supervision by a guardian is necessary. If no therapeutic effect is observed or symptoms worsen, discontinue use immediately and consult a doctor. Pregnant or nursing mothers should carefully weigh the risks and benefits of using this medication and use it only when necessary. Children are at a higher risk of side effects than adults, so use the minimum effective dose only. Overuse of this medication for extended periods can lead to adrenal insufficiency, Cushing's syndrome, and other systemic side effects, so caution is needed. Psoriasis patients should avoid long-term high-dose use as skin symptoms may worsen. If there is blurred vision or visual disturbances, seek evaluation from an ophthalmologist immediately. This medication should not be used for ophthalmic purposes and should not be used outside of treatment purposes after makeup or shaving. Occlusive dressings must be used under a doctor's supervision, and the affected area should be cleaned beforehand. Store out of reach of children, and keep in the original container.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling, chest tightness, difficulty breathing, cold sweat, pallor, high fever, severe rash, blisters, skin peeling, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory issues accompanied by cough and fever, yellowing of the skin or eyes, profound lethargy, sudden and severe headache, thunderclap headache, seizures, altered consciousness, visual disturbances, paralysis, considerably reduced urine output, systemic

Mild side effects

  • Skin irritation
  • pain
  • fever
  • burning sensation
  • itching
  • rash
  • erythema
  • flushing
  • dry skin
  • pustular dermatitis
Show 23 more
  • heat rash
  • wound deterioration
  • pressure sores
  • pustulosis
  • skin discoloration
  • hypertrichosis
  • acneiform rash
  • hypopigmentation
  • perioral dermatitis
  • allergic contact dermatitis
  • skin softening
  • secondary infection
  • skin atrophy
  • striae
  • folliculitis
  • eczema
  • blurred vision
  • headache
  • protruding of the fontanelle
  • delayed weight gain
  • growth retardation
  • intracranial hypertension
  • blurred vision

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to prevent air or moisture from entering, and it is best to store it at room temperature between 1 and 30 degrees Celsius. This way, the medication's efficacy can be maintained and degradation prevented.

Appearance and packaging

Appearance

White creamy preparation

Package unit

30 grams / tube

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

  • QI've heard that prolonged use can thin the skin; is that true?

    The instructions state that skin atrophy, stripes, and skin discoloration are possible adverse reactions. If you notice these changes, stop using the product and consult a doctor or pharmacist, and if you need to use it over a large area for a long time, seek advice in advance.

    Answers 1 · 2026.09.14

  • QHow many times a day should I apply it to the eczema area?

    The instructions indicate to apply an appropriate amount to the affected area 1 to 3 times a day. Since this medication contains a steroid ingredient, do not apply it excessively wide, and consult a doctor or pharmacist if symptoms do not improve.

    Answers 1 · 2026.09.14

For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.