Dangsiga Jeong 5 mg (Dapagliflozin Propanediol Hydrate)

Adult dose

The recommended dosage for this medication is 10 mg once daily for mono-therapy and additional combination therapy with insulin and other blood glucose-lowering agents. When used in combination with insulin or sulfonylureas, lower doses of insulin or insulin secretagogues should be considered. For initial combination therapy, the initial recommended dose of this medication is either 5 mg or 10 mg once daily.

Child dose

The efficacy and safety of dapagliflozin in children under 18 years of age have not been established.

This medication should not be used in patients with a history of hypersensitivity, type 1 diabetes mellitus, diabetic ketoacidosis, or patients undergoing dialysis. It should be administered cautiously in patients with reduced fluid volume or renal dysfunction, and care must be taken to evaluate and monitor fluid status and kidney function due to the risk of hypotension or acute kidney injury. The efficacy of blood sugar control varies depending on kidney function, so it is not recommended for blood sugar control purposes in patients with moderate or severe kidney impairment. Adverse reactions such as genital infections, urinary tract infections, hypoglycemia, decreased fluid volume, and diabetic ketoacidosis may occur while taking this medication, and patients should consult healthcare professionals immediately if any symptoms arise. Particular caution is needed for the elderly and patients taking diuretics due to a higher risk of hypotension and decreased fluid volume. Pregnant or breastfeeding women should avoid using this medication, and if pregnancy is confirmed, administration should be stopped immediately. This medication may increase the risk of hypoglycemia when used with insulin or sulfonylureas, so dosage adjustments of these medications may be necessary. During treatment, blood sugar levels as well as symptoms of ketoacidosis should be closely monitored, and healthcare professionals should be notified immediately if symptoms of dehydration or hypotension occur. Additionally, this medication may increase urinary output, leading to reduced fluid volume, so regular checks on fluid status are necessary. In case of overdose, there is no specific antidote, so appropriate symptomatic treatment should be provided. Patients should be cautious of hypoglycemic symptoms when driving or operating machinery. Finally, this medication has not been established for safety and efficacy in children, so it should not be used and must be kept out of reach of children.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, mucosal pain in mouth/eyes, trouble breathing or shortness of breath, asthma attacks, cough + fever accompanied respiratory abnormalities, yellowing of skin or eyes (jaundice), profound drowsiness, sudden and severe headache, thunderclap headache, seizures, confusion of consciousness, visual disturbances, paralysis, urine

Mild side effects

Vulvovaginitis, balanitis and related genital infections, urinary tract infections, fungal infections, hypoglycemia, thirst, dizziness, constipation, dry mouth, back pain, dysuria, polyuria, nocturia, interstitial nephritis, elevated hematocrit, reduced renal creatinine clearance at treatment initiation, dyslipidemia, elevated serum creatinine, elevated serum urea, weight loss, gastroesophageal reflux disease, upper abdominal pain, diverticulitis, bowel perforation, acute pancreatitis, chronic pancreatitis,

This medication should be stored in a tightly closed container to prevent exposure to air or moisture. It is important to maintain storage temperatures between 1 and 30 degrees Celsius to safely retain the medication's efficacy.

Appearance

Yellow round film-coated tablet

Package unit

28 tablets/bottle, 30 tablets/bottle, 28 tablets/box [7 tablets/Alu-Alu x 4]