Question 1

What are the indications and effects of K-Cap 25 mg (Tegoprazan)?

Accepted Answer

This medication is used to treat erosive and non-erosive gastroesophageal reflux disease and is also effective in treating gastric ulcers. Additionally, it is used in combination with antibiotics for the eradication of Helicobacter pylori infection in patients with peptic ulcers or chronic atrophic gastritis. It is used as maintenance therapy at a dosage of 25 mg after treating erosive gastroesophageal reflux disease to prevent symptom recurrence. It helps with complex gastrointestinal diseases and is effective in improving symptoms.

Question 2

What are the dosage and administration instructions for K-Cap 25 mg (Tegoprazan)?

Accepted Answer

Administer 50 mg orally once daily for 4 weeks. If esophagitis has not healed or symptoms persist, administer for an additional 4 weeks.
Administer 50 mg orally once daily for 4 weeks.
Administer 50 mg orally once daily for 8 weeks.
Administer this medicine 50 mg with amoxicillin 1 g and clarithromycin 500 mg orally twice daily for 7 days.
Administer 25 mg orally once daily.
This medicine may be administered without regard to meals.
Patients with hepatic impairment: No dosage adjustment is required in patients with mild hepatic impairment according to the Child-Pugh classification.

Question 3

What are the side effects of K-Cap 25 mg (Tegoprazan)?

Accepted Answer

nausea, diarrhea, dyspepsia, nasopharyngitis, viral upper respiratory infection, chest discomfort, epigastric pain, abdominal discomfort, constipation, abdominal pain, abdominal distension, vomiting, belching, lower abdominal pain, gastric ulcer, anal bleeding, erosive duodenitis, bloating, gastric polyp, gastroesophageal reflux disease, intestinal metaplasia, hematemesis, hemorrhoids, melena, folliculitis, bacterial gastroenteritis, latent tuberculosis, increased alanine aminotransferase, increased gamma-glutamyl transferase, increased blood bilirubin, increased aspartate aminotransferase, increased blood creatine phosphokinase, presence of hematuria, positive urine red blood cells, increased blood gastrin, increased blood triglycerides, fatigue, ligament sprain, concussion, abrasions, foot fractures, joint injuries, muscle sprain, myalgia, arthralgia, tendinitis, headache, dizziness, vascular edema, dermatitis, seborrheic dermatitis, cough, oropharyngeal pain, throat irritation, vaginal discharge, vulvar pruritus, breast calcification, uterine adenomyosis, ovarian cyst, biliary stones, liver cyst, hypertonic bladder, nocturia, renal cyst, gastric adenocarcinoma, breast cancer, gastrointestinal adenoma, uterine leiomyoma, ventricular premature contractions, lymphadenitis, anemia, insomnia, dental implants, otalgia, diabetes mellitus, hypertension, thyroid cyst, diarrhea, epigastric pain, abdominal distension, dysgeusia, headache, urticaria, dry mouth, anal incontinence, duodenitis, passage of bloody stool, oral sensory disturbance, migraine, drowsiness, pruritus, erythema, rash, drug rash, toxic skin rash, cystitis, shingles, miliaria, sinusitis, tonsillitis, myasthenia, chest pain, dorsolumbar pain, musculoskeletal stiffness, vocal impairment, palpitations, flushing, facial flushing, choroiditis, retinal disorders, facial paralysis, sensory disturbances, bronchitis, periodontitis, chronic gastritis, erosive gastritis, increased blood creatine phosphokinase, wet cough, chronic urticaria, diastolic dysfunction, hearing loss, thyroid nodule, hepatic steatosis, nephrolithiasis, limb pain

Question 4

What precautions should be taken when using K-Cap 25 mg (Tegoprazan)?

Accepted Answer

This medicine should not be used by individuals who have an allergic reaction to this medicine or any of its components, or who have had such experiences in the past.

Patients taking medications that include atazanavir, nelafenavir, or rilpivirine should also not use this medicine concurrently.

It is safer for pregnant or breastfeeding women not to take this medicine.

Patients with severely impaired liver function or reduced kidney function should use this medicine cautiously, and the safety for patients with kidney impairment is still uncertain.

Elderly individuals should be careful as liver and kidney functions may be weakened.

During the use of this medicine, gastrointestinal related symptoms such as nausea, diarrhea, and dyspepsia, as well as neurological symptoms like headache and dizziness may occur.

Rarely, various side effects such as skin rash, increased blood pressure, and fatigue have been reported. If any unusual symptoms appear, consult with a healthcare professional.

Long-term use may lead to vitamin B12 deficiency; hence, regular testing is necessary.

Long-term use may also lead to gastric polyps, so it is important to minimize the treatment duration and dose.

This medication suppresses gastric acid secretion and may slightly increase the risk of gastrointestinal bacterial infections; if diarrhea persists, consult with a specialist.

The effect on driving or operating machinery is unclear, but caution is necessary according to symptoms.

Other medications that may affect absorption should be disclosed to the healthcare provider during use.

Severe symptoms from overdose are rare, but if symptoms occur, visit a medical institution immediately.

Lastly, the safety and efficacy of this medicine in children and adolescents have not been sufficiently verified, so caution is needed in its use.

Keep this medicine out of the reach of children and do not transfer it to other containers.

K-Cap 25 mg (Tegoprazan)

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Efficacy & effects

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Adult dose

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