Medication info
Nuborojet Tablet 40/5/5/10 mg

Nuborojet Tablet 40/5/5/10 mg

Prescription medicationTablet경구
Ingredient · strength
Telmisartan›40mg / 1 tabletRosuvastatin Calcium Micronized›5.2mg / 1 tabletEzetimibe›10mg / 1 tabletS-Amlodipine Besylate Dihydrate›7.38mg / 1 tablet
Manufacturer / importer
(주)종근당
Appearance
Pale yellow oval film-coated tablet
Packaging
30 tablets per bottle
Approval status
Active

MFDS item code 202203011 · Approved 2022.07.20 · Insurance code 643309100

Summary

Main use
Additional treatment for hypertension and dyslipidemia (cholesterol, etc.)
Who takes it
Adults
Adult dose
This medication is to be administered only to adults, with one tablet taken once daily, regardless of meals, taken with water. It is recommended to take it at the same time every day if possible. The recommended dosage for telmisartan/S-amlodipine (amlodipine) combination is once daily and should be individualized for each patient. The rosuvastatin/ezetimibe combination is given for primary hypercholesterolemia at doses ranging from 5/10 mg to 20/10 mg once daily, starting with an initial dose.

Ingredients

Manufacturer
(주)종근당

Efficacy & effects

Additional treatment for hypertension and dyslipidemia (cholesterol, etc.)

  • Essential hypertension
  • primary hypercholesterolemia
  • heterozygous familial hypercholesterolemia
  • non-familial hypercholesterolemia
  • mixed dyslipidemia
  • elevated total cholesterol
  • increased LDL cholesterol
  • elevated Apo B protein
  • increased triglycerides
  • elevated non-HDL cholesterol
View approved original text

This medication is suitable for patients who require the combined use of telmisartan and S-amlodipine (amlodipine), as well as rosuvastatin and ezetimibe. It is used for additional blood pressure and lipid control in cases where hypertension is not adequately controlled with monotherapy and in patients with high blood cholesterol levels due to dyslipidemia. It is particularly beneficial for patients with essential hypertension and mixed types of dyslipidemia. This medication lowers total cholesterol, LDL cholesterol, Apo B protein, triglycerides, and non-HDL cholesterol while increasing good cholesterol, HDL cholesterol, thereby improving vascular health. Therefore, it is effectively used for those who need to control both blood pressure and blood lipid levels.

How to take

Adult dose

This medication is to be administered only to adults, with one tablet taken once daily, regardless of meals, taken with water. It is recommended to take it at the same time every day if possible. The recommended dosage for telmisartan/S-amlodipine (amlodipine) combination is once daily and should be individualized for each patient. The rosuvastatin/ezetimibe combination is given for primary hypercholesterolemia at doses ranging from 5/10 mg to 20/10 mg once daily, starting with an initial dose.

Precautions

This medication can cause serious problems for the fetus or newborn if used during pregnancy, so it should be discontinued immediately upon confirmation of pregnancy. If severe muscle pain, weakness, or muscle cramps occur while taking this medication, notify your doctor immediately, and necessary tests may be conducted to check for muscle damage. Patients with liver dysfunction or liver disease must consult a doctor before using this medication, and liver function tests must be performed regularly. Caution is required for patients with decreased kidney function or severe kidney disease before taking this medication, and kidney function tests must be performed frequently. This medication should not be administered to patients with specific allergic reactions or lactose intolerance, and it is essential to inform your doctor about any hypersensitivity. Drug interactions may occur when taken with other medications, so inform your doctor or pharmacist about any medications currently being taken. As a medication that lowers blood pressure, hypotensive symptoms may occur; thus, if dizziness or fainting occurs, consult medical personnel immediately. There is a risk of hyperkalemia, so potassium levels in the blood must be monitored regularly, and caution should be taken not to excessively consume potassium supplements or potassium-rich foods. It is advisable to avoid or limit alcohol during the treatment period, and caution is required as drowsiness or dizziness may occur while driving or operating machinery. If muscle-related abnormal symptoms occur, discontinue use immediately and consult with medical personnel, especially if muscle pain is accompanied by fever, immediate medical attention is needed. This medication may affect liver and kidney functions; thus, regular blood tests and health checks are essential. If an allergic reaction such as skin rash, itching, swelling of the face or neck occurs during treatment, discontinue use immediately and visit a medical institution.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with high fever, blisters, skin peeling, pain in mucous membranes of mouth/eyes, shortness of breath or difficulty breathing, asthma attack, respiratory abnormalities with cough + fever, jaundice (yellowing of skin or eyes), extreme lethargy, sudden and severe headache, lightning headache, seizures, confusion of consciousness, visual disturbances, paralysis, urinary changes

Mild side effects

  • Abdominal pain
  • diarrhea
  • vomiting
  • indigestion
  • headache
  • dizziness
  • fatigue
  • malaise
  • muscle pain
  • muscle cramps
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  • rash
  • itching
  • hair loss
  • constipation
  • dry mouth
  • palpitations
  • weakness
  • urination disorders
  • nocturia
  • cough
  • nasal congestion
  • oropharyngeal pain
  • rhinitis
  • elevated blood sugar
  • thrombocytopenia
  • elevated creatine kinase levels
  • increased creatinine
  • elevated uric acid
  • increased blood pressure
  • generalized pain
  • joint pain
  • erectile dysfunction
  • sensory abnormalities

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to prevent air or moisture from entering. It is advised to maintain storage temperatures at room temperature between 1 and 30 degrees Celsius. This way, the efficacy and safety of the medication can be preserved for a long time.

Appearance and packaging

Appearance

Pale yellow oval film-coated tablet

Package unit

30 tablets per bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.