Rabeum Duo Tablet 20/800 mg

Adult dosage

For gastric ulcers and duodenal ulcers: Administer 20/800 mg orally once daily according to symptoms. It is typically administered for up to 8 weeks for gastric ulcers and up to 6 weeks for duodenal ulcers. For erosive or ulcerative gastroesophageal reflux disease: Administer 20/800 mg orally once daily for 4 to 8 weeks. If treatment is not effective after 8 weeks of proton pump inhibitors (PPI), an additional 20/800 mg may be administered orally twice daily for another 8 weeks. However, the 20/800 mg twice daily regimen is limited to patients with confirmed severe mucosal damage. For long-term maintenance therapy of gastroesophageal reflux disease: Administer 20/800 mg orally daily according to the patient. Patients with liver impairment: Adverse reactions of hepatic encephalopathy have been reported in patients with liver cirrhosis. Therefore, it should be administered with caution. For children: The safety for children has not been established. For the elderly: Caution is necessary due to the possibility of decreased liver function.

Children's dosage

The safety for children has not been established.

This medication should not be administered to patients with known allergies to specific ingredients or those who have experienced hypersensitivity reactions previously. Patients taking Atazanavir or Rilpivirine should also avoid using this medication. It is safer for pregnant or breastfeeding women to refrain from taking this medication. Caution is required when administering this medication to patients with liver or kidney function issues, elderly patients, and those with reduced heart or lung function. Patients with electrolyte imbalances or certain syndromes should also be cautious. Additionally, caution is advised for those allergic to dyes included in this medication. Various side effects may occur during use, including skin rash, itching, blood abnormalities, liver dysfunction, heart problems, gastrointestinal symptoms, and neurological issues, and symptoms should be discussed with a physician immediately. Regular blood and liver function tests are especially important. This medication may increase the risk of bone fractures with long-term use due to suppression of stomach acid secretion and may lead to hypomagnesemia, so magnesium levels should be checked when necessary. There may be an increased risk of gastrointestinal bacterial infections, so patients should inform healthcare providers if diarrhea persists. Caution is advised while driving or operating machinery as drowsiness may occur. This medication may interact with other medications, so patients must inform healthcare providers about any medications they are taking. For pregnant or breastfeeding women, the safety of this medication has not been established, so it is advisable not to take it. Elderly patients may experience side effects more frequently due to impaired liver function, so caution and possibly discontinuation of use are necessary if symptoms arise. The safety of this medication has not been established for children, and there is no experience with its use. There is no specific antidote for overdose, so appropriate treatment should be performed according to symptoms, and the tablet should be swallowed whole without chewing or crushing. It should be kept out of reach of children and not transferred to another container.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, hypotension, skin rash, dry skin, toxic epidermal necrolysis (Lyell syndrome), mucocutaneous syndrome (Stevens-Johnson syndrome), pulmonary abnormalities, pulmonary dysfunction, systemic allergic reactions, anaphylaxis, shock, liver abnormalities (jaundice), fulminant hepatitis, liver dysfunction, jaundice, serious neurological symptoms (severe headache, seizures, consciousness confusion, visual disturbances, paralysis)

Mild side effects

• Rash
• itching
• decreased erythrocytes
• decreased leukocytes
• increased leukocytes
• increased eosinophils
• increased neutrophils
• decreased lymphocytes
• anemia
• petechial hemorrhage

This medication should be stored in a tightly sealed container to avoid moisture and kept at a temperature between 1 and 30 degrees Celsius. Storing it this way helps maintain the effectiveness of the medication and prevents it from deteriorating.

Appearance

White round tablet

Package unit

28 tablets/bottle