Medication info
Exigluese Tablet

Exigluese Tablet

Prescription medicationTablet
Ingredient · strength
Sitagliptin Phosphate Hydrate›128.5mg / 1 tabletDapagliflozin›10mg / 1 tablet
Manufacturer / importer
(주)종근당
Appearance
Pink round film-coated tablet
Packaging
30 tablets/bottle, 3 tablets/bottle, 30 tablets/box [(10 tablets/PTP) x 3]
Approval status
Active

MFDS item code 202202855 · Approved 2022.07.11 · Insurance code 643309030

Summary

Main use
Improvement of blood sugar control in type 2 diabetes
Who uses it
Adults
Adult dosage
This medication can be administered to patients taking sitagliptin 100 mg and dapagliflozin 10 mg, at a dose of 1 tablet once daily regardless of meals. The tablet should be swallowed whole.

Ingredients

Manufacturer
(주)종근당

Efficacy & effects

Improvement of blood sugar control in type 2 diabetes

View approved original text

This medication is suitable for helping patients with type 2 diabetes control their blood sugar when combined with dietary and exercise therapy. It is particularly effective in helping patients manage their blood sugar when sitagliptin and dapagliflozin are used together. This allows for stable blood sugar levels and greatly aids in the management of diabetes.

Dosage and Administration

Adult dosage

This medication can be administered to patients taking sitagliptin 100 mg and dapagliflozin 10 mg, at a dose of 1 tablet once daily regardless of meals. The tablet should be swallowed whole.

Precautions

This medication contains sitagliptin and dapagliflozin as its components and is used for the treatment of diabetes. The sitagliptin component can rarely cause serious allergic reactions, so if symptoms such as rash or difficulty breathing occur, discontinue use immediately and consult a doctor. Additionally, acute pancreatitis, which is inflammation of the pancreas, can occur, so careful observation is required if symptoms such as upper abdominal pain or vomiting occur. The dapagliflozin component can lead to reduced body fluids and lower blood pressure, so it is important to report immediate symptoms of dehydration or dizziness, particularly for patients with poor kidney function or elderly patients. This medication is not recommended for use in patients with type 1 diabetes, diabetic ketoacidosis, or those undergoing dialysis. During treatment, it is necessary to pay attention to symptoms of hypoglycemia, and when using alongside other hypoglycemic agents such as insulin or sulfonylureas, adjustments in dosage may be necessary due to increased risk of hypoglycemia. There is a possibility of genital infections and urinary tract infections, so maintaining cleanliness is essential, and if symptoms of infection occur, medical personnel must be notified immediately. It is advisable for pregnant or breastfeeding women not to use this medication, and its safety has not been confirmed for children under 18 years of age. In case of overdose, there are no specific antidotes, so appropriate treatment should be undertaken based on the symptoms, and dosage adjustments may be necessary for patients with severely impaired kidney function. While taking this medication, caution is needed when driving or operating machinery due to the risk of hypoglycemia. Finally, this medication should be stored out of reach of children and kept in its original container to maintain quality.

Side effects and when to seek care immediately

Serious side effects

  • Hives
  • severe swelling (angioedema)
  • anaphylaxis
  • angioedema
  • Stevens-Johnson syndrome
  • exfoliative skin disease
  • thrombocytopenia
  • acute pancreatitis
  • fatal hemorrhagic pancreatitis
  • necrotizing pancreatitis
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  • acute kidney injury
  • worsening kidney function
  • urinary sepsis
  • pyelonephritis
  • elevation of liver enzymes
  • severe and debilitating arthralgia
  • vesicular pemphigoid
  • rhabdomyolysis
  • pneumonia
  • diabetic complications
  • metabolic acidosis
  • cardiac arrest
  • acute pyelonephritis

Mild side effects

  • Upper respiratory infection
  • nasopharyngitis
  • headache
  • constipation
  • dry mouth
  • back pain
  • dysuria
  • polyuria
  • nocturia
  • vulvar itching
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  • genital itching
  • increased hematocrit
  • dyslipidemia
  • increased serum creatinine
  • increased serum urea
  • weight loss
  • hypoglycemia
  • dizziness
  • diarrhea
  • dry mouth
  • abdominal pain
  • nausea
  • dyspepsia
  • vomiting
  • palpitations
  • insomnia
  • tinnitus
  • itching
  • cold sweat
  • peripheral edema
  • generalized edema
  • hunger

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture, and it is recommended to be kept at room temperature between 1 degree and 30 degrees Celsius. Storing it this way will maintain the medication's effectiveness and allow for safe usage.

Appearance and packaging

Appearance

Pink round film-coated tablet

Package unit

30 tablets/bottle, 3 tablets/bottle, 30 tablets/box [(10 tablets/PTP) x 3]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.