Azelpin 16mg (Azelnidipine)

Adult dose

Adults: Take azelnidipine 8mg or 16mg orally once daily after breakfast. Start with 8mg per dose and adjust the dose as appropriate according to symptoms. Take a maximum of 16mg per day.

This medication should not be used in pregnant women or those who may become pregnant. Patients with a history of allergic reactions to this medication's components should also avoid taking it. Additionally, it should not be taken in combination with certain antifungal agents or HIV treatments due to potential dangers. Patients with very poor kidney function should use it cautiously as blood pressure may drop and worsen kidney function. The safety for patients with severely compromised liver function has not been established, thus it should be administered with caution. Elderly patients are advised to start with a low dose and gradually adjust. Serious side effects such as liver dysfunction or heart rhythm abnormalities may occur, so any abnormal symptoms should be reported immediately. Blood pressure may drop too low, so caution is advised in case of dizziness or lightheadedness, and it is advisable to avoid driving or operating dangerous machinery. This medication may interact with several other drugs, necessitating dose adjustments or discontinuation based on the concomitant medications. Particularly, grapefruit juice may increase the blood concentration of this medication, raising the risk of side effects, so it is safest to avoid it. Its use during pregnancy or breastfeeding is not recommended, and breastfeeding status should be discussed with a doctor. The safety for children has not been thoroughly validated, thus it is best not to use it in pediatric patients. This medication should be stored out of reach of children, and it is important to keep it in a dark place, as it may deteriorate when exposed to light. Additionally, when removing the packaged medication, care should be taken not to incorrectly swallow any packaging material.

Liver dysfunction, jaundice, atrioventricular block, cardiac arrest, bradycardia, dizziness, staggering, hypersensitivity, itching, rash, angioedema, photosensitivity reactions, headache, heaviness in the head, orthostatic hypotension, drowsiness, constipation, dyspepsia, nausea, abdominal pain, diarrhea, gingival hyperplasia, stomatitis, lymphadenopathy, facial flushing, warmth sensation, eosinophilia, elevated ALT, elevated AST, elevated LDH, elevated ALP, elevated total bilirubin, elevated γ-GTP, abnormal liver function, elevated BUN, increased urinary excretion of low molecular weight substances, elevated creatinine, frequent urination, elevated uric acid, elevated total cholesterol, elevated CK, elevated potassium, decreased potassium, malaise, paresthesia, edema, numbness, chylous ascites, myocardial infarction, heart failure, arrhythmia

This medication should be stored in a closed container with silica gel to protect it from light. The proper storage temperature is room temperature, between 1 to 30 degrees Celsius. Storing it this way ensures that the components of the medication do not change and that its effectiveness is maintained for a longer period.

Appearance

Yellow round tablet

Package unit

PTP packaging - 30 tablets/PTP [10 tablets/PTP×3], bottle packaging - 30 tablets/bottle