Crystal Ibuprofen Injection

Adult dosage

Adults can be administered up to a maximum of 3200 mg per day. (1) Adjunctive therapy for moderate to severe pain management with opioids (morphine) Adults (17 years and older): Administer 400 mg-800 mg intravenously every 6 hours as needed. The maximum daily dose can be up to 3200 mg. The administration time should be more than 30 minutes. (2) Antipyretic Adults (17 years and older): 400 mg as needed

Children's dosage

Fever reduction for children (ages 6 months to under 17 years): - For ages 6 months to under 12 years: Administer 10 mg/kg (maximum 400 mg) intravenously every 4–6 hours as needed. The administration time is

This medication should be used with caution in patients with cardiovascular diseases or risk factors, as serious cardiovascular issues such as myocardial infarction or stroke may occur. It may cause serious gastrointestinal adverse reactions such as bleeding, ulcers, and perforations, so elderly patients or those on long-term treatment should be particularly careful. Patients with a history of gastrointestinal ulcers or bleeding, severe liver or kidney impairment, severe hypertension, heart failure, or asthma should not take this medication. Patients with blood disorders, cirrhosis, kidney impairment, cardiac dysfunction, hypertension, systemic lupus erythematosus, ulcerative colitis, Crohn's disease, etc., should use this medication with caution. Pregnant women should not take this medication during late pregnancy due to the risk of ductus arteriosus closure in the fetus, and administration is recommended at the lowest dose and for the shortest duration after mid-pregnancy due to the risk of fetal renal dysfunction and oligohydramnios. Care should be taken as this medication may reduce the cardioprotective effects of aspirin and increase the risk of gastrointestinal bleeding when taken together with aspirin. Adverse effects may include allergic reactions, skin rashes, liver dysfunction, kidney impairment, blood disorders, gastrointestinal issues, difficulty in breathing, headaches, and dizziness, and if symptoms occur, immediate consultation with a doctor is advised. Patients with hypertension should frequently monitor their blood pressure while taking this medication, and patients with heart failure or edema should be cautious due to the potential worsening of fluid retention. It is recommended not to take this medication in conjunction with other non-steroidal anti-inflammatory drugs and not to exceed the recommended dose. In cases of overdose, severe symptoms such as dizziness, vomiting, abdominal pain, renal failure, difficulty in breathing, and hypotension may occur, so the patient should visit a medical institution immediately. Women who are breastfeeding should consider discontinuing breastfeeding or stopping the medication, as it can be transmitted through breast milk and may cause adverse reactions in infants. The safety and efficacy of this medication have not been established in infants under 6 months, and elderly patients require dose adjustments and close monitoring due to decreased body function.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in the mucous membranes of the mouth/eyes, shortness of breath or difficulty breathing, asthma attack, respiratory abnormalities with cough + fever, yellowing of skin or eyes (jaundice), extreme lethargy, sudden and severe headaches, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination

Mild side effects

• Nausea
• vomiting
• bloating
• headaches
• hemolysis
• drowsiness
• peripheral edema
• urination disorders
• anemia
• decreased hemoglobin

This medication should be stored in a sealed container to prevent air and moisture from entering, and it is safe to store at room temperature between 1 and 30 degrees Celsius. Storing it this way helps maintain the medication's effectiveness and prevents degradation.

Appearance

A colorless or pale yellow liquid filled in a colorless transparent plastic vial.

Package unit

100 milliliters/vial, 200 milliliters/vial