Famoprazole 10 mg (Famotidine)

Adult dose

For famotidine, administer 20 mg orally, twice a day (after breakfast, after dinner, or before bedtime). Alternatively, 40 mg can be administered orally once a day (before bedtime). For acute exacerbation of acute gastritis and chronic gastritis, administer 10 mg orally, twice a day (after breakfast, after dinner, or before bedtime). Alternatively, 20 mg can be administered orally once a day (before bedtime). For patients with impaired kidney function:

This medication contains aspartame, an artificial sweetener that is metabolized into phenylalanine in the body. Therefore, patients with phenylketonuria, a hereditary disease, should not take this medication. The daily intake of aspartame should be controlled below the WHO recommended levels, using the minimum amount possible. Patients with hypersensitivity to this medication or similar medications should also avoid taking it. Patients with a history of hypersensitivity, or those with kidney, heart, or liver problems, and the elderly should use this medication with caution. This medication may cause serious allergic reactions, blood abnormalities, skin diseases, liver dysfunction, muscle problems, heart arrhythmias, neurological abnormalities, nephritis, pneumonia, and other serious side effects, so symptoms should be monitored closely. If any adverse effects occur, discontinue use immediately and consult a healthcare professional. Periodic blood tests and kidney and liver function tests should be conducted to monitor for any abnormalities during treatment. This medication dissolves in the mouth but is not absorbed through the oral mucosa, so it must be swallowed with saliva or water. Caution is needed when this medication is taken concurrently with phosphate compounds in dialysis patients, as it may reduce calcium carbonate efficacy. This medication may interact with certain antifungal agents or some anticancer drugs, so caution is necessary when taken together. The elderly may require a reduced dosage or increased dosing interval due to decreased renal function, as the medication may remain longer in the body. Pregnant women should only take this medication if the benefits outweigh the risks, and breastfeeding mothers should discontinue nursing as the medication can pass into breast milk. The safety of this medication for children has not been sufficiently established, so caution is advised. For orally disintegrating tablets, they can be placed on the tongue to dissolve, and can be taken using saliva alone, but should not be taken without water while lying down. Symptoms of stomach cancer may be masked while taking this medication, so it should be taken only after confirming the absence of malignancy.

Serious side effects

Shock, hypersensitivity (anaphylaxis, difficulty breathing, generalized flushing, angioedema, urticaria), pancytopenia, agranulocytosis, aplastic anemia, hemolytic anemia, thrombocytopenia, Stevens-Johnson syndrome, Lyell's syndrome (toxic epidermal necrolysis), liver dysfunction, jaundice, rhabdomyolysis, QT prolongation, ventricular tachycardia (including Torsades de Pointes), ventricular fibrillation, altered consciousness, seizures, interstitial nephritis, acute renal failure, interstitial pneumonia, heart failure

Mild side effects

• Rash
• urticaria
• facial swelling
• leukopenia
• eosinophilia
• constipation
• diarrhea
• nausea
• vomiting
• abdominal bloating

This medication should be stored in a tightly closed container to prevent exposure to air or moisture. Additionally, the medication should be stored at room temperature, which is not too hot or cold, specifically between 1 to 30 degrees Celsius.

Appearance

White round orally disintegrating tablet

Package unit

PTP - 100 tablets/box [10 tablets x 10 PTP], Bottle - 100 tablets/bottle