Polcox Capsule 2 mg (Polmacoxib)

Adult dose

Before administering this medicine, consider the potential risks and benefits of this medicine and other alternative treatments. Cardiovascular risk increases with higher doses and longer exposure to this medicine; therefore, administer it for the shortest possible duration. Efficacy beyond 6 weeks and the safety of long-term administration beyond 6 months have not been established. Adverse reactions such as hypertension, angina, and edema may occur during treatment with this medicine. Therefore, during treatment, the need to continue therapy based on symptom relief and the response to treatment should be reassessed regularly at least once a month. Adults: The recommended dose is 2mg once daily, taken after a meal. Do not exceed a daily dose of 2mg. If there is no therapeutic benefit at the recommended dose, discontinue this medicine and consider an appropriate alternative treatment. Patients with hepatic or renal impairment: Do not administer this medicine because there is no experience with its use.

Patients who regularly consume more than three alcoholic drinks per day should consult with a doctor or pharmacist before taking this medication. Otherwise, the risk of gastric bleeding may increase. This medication can affect the cardiovascular system, potentially increasing the risk of serious cardiovascular diseases such as myocardial infarction or stroke. Particularly, in patients with cardiovascular diseases or risk factors, it should only be taken at the minimum effective dose and for a short duration. Additionally, if any cardiovascular symptoms arise, immediate consultation with a doctor is necessary. Serious issues such as gastrointestinal bleeding, ulcers, and perforations may occur, so caution is warranted for patients with a history of gastrointestinal disorders or the elderly. If symptoms such as epigastric pain, indigestion, black stools, or hematemesis occur, medical attention should be sought promptly. Patients with specific allergies, or patients with liver, kidney, or heart function issues, pregnant or breastfeeding women, and individuals with certain conditions should not take this medication. Furthermore, patients with asthma, hypertension, edema, or diabetes should consult a doctor before taking this medication. While taking this medication, adverse reactions such as headaches, indigestion, elevated blood pressure, edema, skin rashes, and shortness of breath may occur; it is important to inform healthcare providers immediately if these symptoms arise. This medication may affect liver and kidney function, so patients taking it for an extended period should have regular blood tests and liver and kidney function tests. If symptoms of liver dysfunction arise, use should be discontinued. This medication can interact with other drugs, so if you are currently taking other medications, be sure to inform your doctor or pharmacist. Caution is required when taken with medications metabolized by the liver, blood pressure medications, anticoagulants, diuretics, or anticancer drugs. Women who are pregnant or planning to become pregnant should avoid this medication, and breastfeeding women should consult a specialist before use. The safety for children and adolescents under 18 years has not been established, so it is not advisable to use this medication in that population. Elderly patients may have decreased liver, kidney, and heart function, thus special precautions and monitoring are necessary when taking this medication. In case of overdose, symptoms may include lethargy, drowsiness, nausea, vomiting, and upper abdominal pain, which may require emergency treatment. Therefore, it is vital to adhere to the recommended dosage and usage.

Gastrointestinal bleeding, serious cardiovascular thrombotic events, myocardial infarction, stroke, upper abdominal pain, dyspepsia, nasopharyngitis, pneumonia, tinea, bronchitis, soft tissue infection, abscess, herpes zoster, influenza, syphilis, urinary tract infection, onychomycosis, colon adenoma, anemia, skin papilloma, eosinophilia, hypersensitivity reaction, chemical allergy, diabetes, hypercholesterolemia, hyperkalemia, depressive mood, major depressive disorder, headache, insomnia, paresthesia, conscious depressive state, dizziness, drowsiness, lethargy, Alzheimer-type dementia, tremor, eyelid edema, eyelid swelling, blepharitis, eyelid spasm, dryness of the eyes, keratitis, macular hole, ear discomfort, positional vertigo, palpitations, angina, angle closure, myocardial ischemia, elevated blood pressure, arrhythmia, hypertension, facial flushing, abnormal blood pressure, cough, shortness of breath, asthma, runny nose, oropharyngeal pain, wet cough, rhinitis, allergic rhinitis, upper abdominal pain, diarrhea, nausea, abdominal pain, vomiting, bowel motility disorder, irritable bowel syndrome, stool discoloration, food poisoning, gastric ulcer, gingivitis, dental disorders, dry mouth, enteritis, upper abdominal discomfort, gastritis, abdominal discomfort, lower abdominal pain, aphthous stomatitis, constipation, gastroesophageal reflux disease, colon polyps, esophagitis, hyperbilirubinemia, facial swelling, urticaria, erythema, neurodermatitis, itching, generalized itching, dry eczema, arthralgia, back pain, flatfoot, joint swelling, neck pain, limb pain, plantar fasciitis, musculoskeletal pain, intervertebral disc herniation, muscle cramps, frequent urination, chronic renal failure, microalbuminuria, ureteral stones, breast pain, chest discomfort, facial swelling, edema, peripheral edema, fatigue, generalized edema, influenza-like illness, weight gain, asthenia, thirst, contusion, abrasion, laceration, traffic accident, spinal compression fracture, chills, fever, insect bite, concussion, ligament rupture, ligament sprain, wound, wrist fracture, hot sensation, drug overdose, neutrophilia, decreased unsaturated iron binding capacity, prolonged prothrombin time, decreased hemoglobin, increased alanine aminotransferase, increased aspartate aminotransferase, increased creatine phosphokinase, increased serum creatinine, stroke, sensory abnormalities, sensory impairment, rash, drug rash, skin erosion, tachycardia, conjunctival congestion, gastrointestinal disorder, abdominal distension, loss of appetite, daydreaming, dysuria, lethargy, drowsiness, nausea, vomiting, upper abdominal pain, hypertension, acute kidney failure, respiratory depression, coma

This medication should be stored in a tightly sealed container to prevent air and moisture from entering, ideally at a cool room temperature between 1°C and 30°C. Storing it this way will help maintain its effectiveness for a longer period.

Appearance

A white to light yellow powder contained in white hard capsules.

Package unit

30 capsules/bottle, 100 capsules/bottle