Clozartan Tablet 50/12.5 mg (Losartan, Chlorthalidone)

Adult dose

The recommended dosage for this medication is 1 tablet once daily, taken with water regardless of meals. It is advisable to take it at the same time every day (e.g., in the morning). For elderly patients (75 years and older), the recommended initial dose of Losartan potassium is 25 mg once daily; however, this medication cannot deliver that dosage, so initiation of treatment is not recommended. In cases of renal impairment (creatinine clearance

This medication can cause serious harm to the fetus if taken during pregnancy, especially during the second and third trimesters, so it should be discontinued immediately upon confirmation of pregnancy. Patients with impaired liver function or cirrhosis are at risk of hepatic encephalopathy when taking this medication, so caution is advised. This medication should not be used in patients with severe kidney disease, as some components may accumulate in the body and cause problems. It should be avoided by those with hypersensitivity to this medication or its components and certain liver or kidney diseases. Elderly patients, those with electrolyte imbalances, and patients with heart or vascular diseases should use this medication cautiously, and periodic blood pressure and blood tests are required during treatment. This medication may cause side effects such as dizziness, headache, dyspepsia, skin rash, and other abnormalities; if unusual symptoms occur, it is important to consult a healthcare professional. Serum potassium levels may increase, so co-administration with potassium supplements or potassium-sparing diuretics is not recommended. Care should be taken when combining this medication with other antihypertensives, diuretics, non-steroidal anti-inflammatory drugs (NSAIDs), etc., as interactions may result in side effects. Pregnant and nursing women should not take this medication; if necessary, breastfeeding should be discontinued. Safety in children has not been established, so it is not recommended. Overdosage may result in hypotension, tachycardia, electrolyte imbalances, etc., and immediate medical treatment is required. Keep this medication out of the reach of children and do not transfer it to another container.

Serious side effects

• Urticaria
• angioedema
• difficulty breathing
• liver dysfunction
• jaundice
• acute renal failure
• severe hepatitis
• serious allergic reactions
• angioedema
• myocardial infarction

Mild side effects

• Dizziness
• headache
• abdominal bloating
• chronic gastritis
• dyspepsia
• epigastric pain
• gastroesophageal reflux disease
• asthenia
• gastroenteritis
• shingles

Store this medication in a sealed container to protect it from air and moisture. It is best to maintain a storage temperature between 1 and 30 degrees Celsius.

Appearance

White oval film-coated tablet

Package unit

30 tablets/bottle