Medication info

DuoWell A Plus Tablets 40/10/10/5 mg

Prescription medicationTablet경구
Ingredient · strength
Telmisartan›40mg / 1 tabletRosuvastatin Calcium›10.4mg / 1 tabletEzetimibe›10mg / 1 tabletAmlodipine Besylate›6.944mg / 1 tablet
Manufacturer / importer
(주)유한양행
Appearance
Pink oval film-coated tablets
Packaging
30 tablets/box [6 tablets/PTP X 5]
Approval status
Active

MFDS item code 202202140 · Approved 2022.05.20

Summary

Main use
Adjunctive treatment for hypertension and dyslipidemia (such as hypercholesterolemia)
Who takes it
Adults
Adult dose
This medication is only administered to adults and the dosage should be individualized for each patient. The recommended dose is 1 tablet once daily, to be taken with water regardless of meals. It is recommended to take it at the same time every day (e.g., in the morning). Take this medication whole without chewing, splitting, or crushing. The recommended dosage for the telmisartan/amlodipine combination is once daily. If blood pressure control is inadequate, switching to the combination is recommended under the following circumstances:

Ingredients

Manufacturer
(주)유한양행

Efficacy & effects

Adjunctive treatment for hypertension and dyslipidemia (such as hypercholesterolemia)

  • Essential hypertension
  • primary hypercholesterolemia
  • mixed dyslipidemia
View approved original text

This medication is used for patients who require simultaneous administration of a combination of telmisartan and amlodipine, as well as rosuvastatin and ezetimibe. It helps in cases where sufficient blood pressure control is difficult with monotherapy using amlodipine or telmisartan for essential hypertension. Additionally, it lowers levels of bad cholesterol and triglycerides while raising good cholesterol in patients with primary hypercholesterolemia, familial and non-familial hypercholesterolemia, and mixed dyslipidemia. This medication is effective for the additional management of hypertension and dyslipidemia when used in conjunction with dietary adjustments. Thus, it is used to improve blood pressure and serum lipid levels.

How to take

Adult dose

This medication is only administered to adults and the dosage should be individualized for each patient. The recommended dose is 1 tablet once daily, to be taken with water regardless of meals. It is recommended to take it at the same time every day (e.g., in the morning). Take this medication whole without chewing, splitting, or crushing. The recommended dosage for the telmisartan/amlodipine combination is once daily. If blood pressure control is inadequate, switching to the combination is recommended under the following circumstances:

Precautions

This medication can pose a serious risk to the fetus during pregnancy, so if pregnancy is confirmed, administration should be stopped immediately. Muscle-related side effects may occur, so if symptoms such as myalgia or muscle weakness appear, consult a physician immediately. It may affect liver function; therefore, use this medication cautiously in patients with liver disease or suspected liver dysfunction. It should be administered carefully in patients with impaired renal function, and regular kidney function tests and serum electrolyte tests are important. As this medication lowers blood pressure, symptoms of hypotension may occur, and extra caution is necessary in cases of fluid or sodium deficiency. There may be interactions with other medications, so inform your physician or pharmacist about any other medications you are taking. It is advisable to avoid or limit alcohol consumption while using this medication, and be cautious of dizziness or drowsiness when driving or operating machinery. Do not use this medication if you have had allergies or hypersensitivity reactions to specific components. Elderly patients or patients with certain conditions require careful monitoring and dose adjustments. Regular blood tests and health assessments according to the physician's instructions are safe before and during administration.

Side effects and when to seek care immediately

Serious side effects

Urticaria, angioedema, severe allergic reactions, angioedema (potentially fatal), toxic skin rash, eczema, toxic epidermal necrolysis, Stevens-Johnson syndrome, eosinophilia and systemic symptoms associated with drug reaction syndrome (DRESS), acute renal failure, renal dysfunction, liver function abnormalities, hepatitis, toxic hepatitis, jaundice, rhabdomyolysis, myopathy, thrombocytopenia, severe muscle weakness, ocular muscle weakness, shock, loss of consciousness

Mild side effects

  • Eyelid damage
  • head trauma
  • urinary difficulty
  • flushing
  • chronic gastritis
  • various gastrointestinal disorders
  • hiatal hernia
  • dizziness
  • drowsiness
  • neurodegenerative disorders
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  • orthostatic dizziness
  • migraine
  • fatigue
  • chest pain
  • unusual sensation
  • drug intolerance
  • irritable bowel syndrome
  • esophagitis
  • urticaria
  • rash
  • hair loss
  • dermatitis
  • burning sensation in the skin
  • skin disorders
  • oropharyngeal pain
  • nasal congestion
  • pelvic pain
  • breast cysts
  • eyelid drooping
  • diabetes

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to avoid exposure to air or moisture. Additionally, it should be stored at room temperature between 1 to 30 degrees Celsius, away from extreme heat or cold.

Appearance and packaging

Appearance

Pink oval film-coated tablets

Package unit

30 tablets/box [6 tablets/PTP X 5]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.