Medication info

Duo Well A Plus Tablet 40/5/10/5 Milligrams

Prescription medicationTablet경구
Ingredient · strength
Telmisartan›40mg / 1 tabletRosuvastatin Calcium›5.2mg / 1 tabletEzetimibe›10mg / 1 tabletAmlodipine Besylate›6.944mg / 1 tablet
Manufacturer / importer
(주)유한양행
Appearance
Yellow oval film-coated tablet
Packaging
30 tablets/box [6 tablets/PTP X 5]
Approval status
Active

MFDS item code 202202138 · Approved 2022.05.20

Summary

Main use
Adjunctive treatment for hypertension and dyslipidemia (cholesterol, etc.)
Who takes it
Adults
Adult dose
This medication is restricted to adult use only, and it should be taken once daily, 1 tablet with water, regardless of meals. It is recommended to take it at the same time every day (e.g., in the morning). The recommended dosage for the telmisartan/amlodipine combination is once daily, adjusting doses to 40/5 milligrams, 80/5 milligrams, or 40/10 milligrams based on blood pressure control. Liver impairment patients should limit the daily dosage of telmisartan to 40 milligrams or less and in elderly patients.

Ingredients

Manufacturer
(주)유한양행

Efficacy & effects

Adjunctive treatment for hypertension and dyslipidemia (cholesterol, etc.)

  • Essential hypertension
  • primary hypercholesterolemia
  • mixed dyslipidemia
  • elevated total cholesterol
  • LDL cholesterol
  • Apo B protein
  • triglycerides
  • non-HDL cholesterol
View approved original text

This medication is developed for patients with essential hypertension who are using a combination of telmisartan and amlodipine but are not adequately controlling their blood pressure, as well as for patients taking a combination of rosuvastatin and ezetimibe who need control of dyslipidemia. It is primarily used to treat hypertension and dyslipidemia, assisting in further improvement of blood pressure and cholesterol levels when existing therapies are not controlled. Specifically, this medication is effective in lowering total cholesterol, LDL cholesterol, ApoB protein, and triglycerides while increasing HDL cholesterol levels. Therefore, this medication is suitable for patients who require simultaneous management of blood pressure and lipids, supporting safe and effective treatment.

How to take

Adult dose

This medication is restricted to adult use only, and it should be taken once daily, 1 tablet with water, regardless of meals. It is recommended to take it at the same time every day (e.g., in the morning). The recommended dosage for the telmisartan/amlodipine combination is once daily, adjusting doses to 40/5 milligrams, 80/5 milligrams, or 40/10 milligrams based on blood pressure control. Liver impairment patients should limit the daily dosage of telmisartan to 40 milligrams or less and in elderly patients.

Precautions

This drug can cause severe harm to the fetus if administered during pregnancy, particularly in the second and third trimesters, so it should be discontinued immediately upon confirmation of pregnancy. If symptoms of myalgia or muscle weakness occur, notify a physician immediately and undergo testing; if severe, discontinue the drug. This medication should not be administered to patients with severely impaired liver or kidney function, certain muscle disorders, or certain liver diseases. It should also be avoided in patients with excessively low blood pressure or severely compromised cardiac function, and those in an unstable state following acute myocardial infarction. There may be interactions with other drugs, so you must inform your doctor or pharmacist of any medications currently being taken. This medication has blood pressure-lowering effects, which may lead to symptoms of hypotension; caution should be exercised if dizziness or light-headedness occurs. If symptoms of liver function impairment or muscular abnormalities (such as myalgia or muscle spasms) arise, get tested immediately and discontinue the drug if necessary. During the course of this medication, it is important to regularly conduct blood tests to check liver function, kidney function, and muscle enzyme levels. Caution should be exercised if there is excessive alcohol consumption or a history of liver disease, and if liver function impairment is suspected, consult medical personnel immediately. This medication may cause allergic reactions or skin rashes, so if any abnormal symptoms occur, the drug should be discontinued immediately and medical personnel should be informed. Dizziness or drowsiness may occur; caution is needed when driving or operating dangerous machinery. This drug contains lactose, so patients with lactose intolerance or related genetic disorders should not take it. Women of childbearing age who require contraception must use appropriate contraceptive methods during the course of this medication. If sudden muscle pain, weakness, malaise, fever, etc., occur while taking this medication, consult a doctor immediately.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with high fever, blisters, skin peeling, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attacks, cough and fever accompanied respiratory distress, yellowing of skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, altered consciousness, visual disturbances, paralysis, urinary issues.

Mild side effects

  • Eyelid injury
  • head injury
  • urinary difficulty
  • flushing
  • chronic gastritis
  • various gastrointestinal disturbances
  • hiatal hernia
  • dizziness
  • somnolence
  • neurodegenerative disorders
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  • positional vertigo
  • migraine
  • infections
  • upper respiratory infections
  • urinary tract infections
  • pharyngitis
  • sinusitis
  • anemia
  • thrombocytopenia
  • eosinophilia
  • hyperkalemia
  • hypoglycemia
  • depression
  • insomnia
  • anxiety
  • syncope
  • visual disturbances
  • dizziness
  • bradycardia
  • tachycardia
  • hypotension
  • orthostatic hypotension
  • abdominal pain

Not everyone experiences these, and they can vary from person to person.

Storage

This drug may be sensitive to air or moisture, so it should be stored in a tightly sealed container. The storage temperature should be maintained at room temperature between 1 and 30 degrees Celsius, and it is advisable to avoid extremely hot or cold places.

Appearance and packaging

Appearance

Yellow oval film-coated tablet

Package unit

30 tablets/box [6 tablets/PTP X 5]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.