Janumax MXR Controlled-Release Tablet 50/500 mg

Adult dose

The dosage of this medication is determined based on the patient's current treatment regimen, efficacy, and tolerability, without exceeding the maximum recommended daily doses of sitagliptin 100 mg and metformin 2000 mg. This medication is taken once daily with dinner, and the dose should be gradually increased. To maintain its controlled-release characteristics, it should be swallowed whole and not divided, crushed, ground, or chewed. This medication 10

This medication is used for the treatment of diabetes and contains two active ingredients, sitagliptin and metformin. When taking this medication, there is a possibility of hypersensitivity reactions; if symptoms such as allergic reactions, skin rashes, or difficulty breathing occur, discontinue use immediately and consult a doctor. There is a risk of serious inflammation of the pancreas, known as acute pancreatitis, so if abdominal pain, vomiting, or severe abdominal pain occur, you should visit a hospital immediately. Patients with poor kidney function or those experiencing severe infections or dehydration should not take this medication. Additionally, if you are receiving iodinated contrast agents for radiographic examinations, this medication should be suspended for a period around the examination, and you should resume taking it only after confirming normal kidney function. Women who are pregnant or breastfeeding, as well as children under 18 years of age, should not use this medication as a precaution. During the course of this medication, be cautious of symptoms of hypoglycemia, especially when taken with other hypoglycemic agents or insulin, as the risk of hypoglycemia may increase. The metformin component can rarely cause severe metabolic disturbances known as lactic acidosis, so it should be discontinued in cases of severe dehydration, acute illness, or liver dysfunction. It is important to regularly monitor kidney function, blood tests, and vitamin B12 levels for any abnormalities. If you consume alcohol excessively, the risk of lactic acidosis may increase, so it is advisable to avoid drinking. In case of surgery, this medication should be discontinued 48 hours prior to the surgery, and resuming treatment should only occur after confirming normal kidney function post-surgery. Elderly patients may require dose adjustments based on kidney function, and regular monitoring of kidney function is recommended. If you experience any unusual symptoms or discomfort while taking this medication, consult medical personnel immediately.

Serious side effects

Urticaria, severe swelling (angioedema), anaphylaxis, severe skin reactions (rash, cutaneous vasculitis, Stevens-Johnson syndrome, bullous pemphigoid), acute pancreatitis, acute kidney failure, liver abnormalities (elevated liver enzyme levels, potential jaundice), severe edema, severe allergic reactions, difficulty breathing, lactic acidosis, severe headache, seizures, altered consciousness, visual disturbances, paralysis, severe hypoglycemia, elevated blood pressure, acute myocardial infarction, acute

Mild side effects

Diarrhea, upper respiratory infection, headache, nausea, vomiting, abdominal pain, nasopharyngitis, constipation, myalgia, limb pain, back pain, interstitial lung disease, pruritus, thrombocytopenia, rhabdomyolysis, decreased vitamin B12, hypoglycemia, joint pain with severe and disabling effects

This medication should be stored in a tightly sealed container to prevent air or moisture from entering. It is best to maintain a storage temperature between 1 degree and 30 degrees Celsius.

Appearance

A bright blue, bilaterally convex, oval-shaped controlled-release film-coated tablet

Package unit

28 tablets/bottle, 56 tablets/bottle, 200 tablets/bottle