Teramet XR Sustained Release Tablet 50/500 milligrams

Adult dose

The dosage for diabetes therapy is determined by considering the current treatment regimen, efficacy, and tolerability of each patient, without exceeding the maximal recommended daily doses of sitagliptin 100 mg and metformin 2000 mg. This medication should be taken once a day during meals, preferably at dinner time, and the dosage should be gradually increased. The sustained-release tablet should be swallowed whole and not split, crushed, ground, or chewed. - This medication 100/1000 mg sustained-release tablet is taken once a day.

This medication contains sitagliptin and metformin components and is used in diabetes treatment. Firstly, although rare, sitagliptin can cause serious allergic reactions; therefore, if symptoms such as itching, rash, or breathing difficulties occur, the medication should be discontinued immediately, and a doctor consulted. Additionally, acute pancreatitis may occur, so if abdominal pain, nausea, or vomiting symptoms develop, notify healthcare professionals promptly. Metformin can rarely cause a serious side effect known as lactic acidosis; thus, if sudden fatigue, muscle pain, difficulty breathing, or abdominal pain occurs, discontinue use immediately and visit a hospital. Patients with reduced kidney function or poor liver function should not take this medication and should undergo regular kidney function tests. This drug should not be administered to patients with specific conditions such as moderate to severe kidney impairment, acute heart failure, severe infections, dehydration, or acute myocardial infarction. Pregnant or breastfeeding women should also avoid using this medication. As there is a risk of hypoglycemia, caution is needed if meal patterns are irregular or intense physical activity is performed, and when used in combination with other blood glucose-lowering agents, dose adjustments may be necessary after consulting with healthcare professionals. During treatment, side effects such as diarrhea, headaches, and upper respiratory tract infections may occur; rarely, joint pain or skin disorders can arise, so if unusual symptoms persist, inform healthcare professionals. Moreover, excessive alcohol consumption should be avoided while taking this medication, and it should be temporarily discontinued before and after surgery. Finally, safety and efficacy have not been established for children (under 18 years) or children under 10 years, so this medication should not be used. Regular blood tests and kidney function tests are needed while taking this medication, and if any unusual symptoms appear, consult with healthcare professionals immediately.

Serious side effects

Hives, severe swelling (edema), anaphylaxis, angioedema, rash, exfoliative skin disorders, Stevens-Johnson syndrome, acute pancreatitis, acute renal failure, severe allergic reactions, severe skin adverse reactions, liver abnormalities (jaundice), severe edema, hypoglycemia, severe hypoglycemia, lactic acidosis, severe headaches, joint pain accompanied by severe symptoms or disabilities, blistering dermatosis, rhabdomyolysis

Mild side effects

• Diarrhea
• upper respiratory tract infection
• headache
• nausea
• vomiting
• abdominal pain
• nasopharyngitis
• constipation
• joint pain
• muscle pain

This medication should be stored in a tightly sealed container to prevent air or moisture from entering. It is best to maintain the storage temperature at room temperature between 1°C and 30°C. Proper storage will help preserve the medication's efficacy and safety.

Appearance

Bright blue, oval-shaped, bilaterally convex sustained-release film-coated tablet

Package unit

28 tablets/bottle, 56 tablets/bottle, 200 tablets/bottle