Medication info
Nepoxil Capsule 500mg (Citrate Iron Compound)

Nepoxil Capsule 500mg (Citrate Iron Compound)

Prescription medicationHard capsuleOral
Ingredient · strength
Ferric Citrate Hydrate›500mg / 1 capsule
Manufacturer / importer
LG Chem Ltd.
Appearance
Hard capsule with red-brown upper and lower parts containing a light brown or light yellow-brown powder
Packaging
Bottle - 45 capsules/bottle, Bottle - 90 capsules/bottle
Approval status
Active

MFDS item code 202201885 · Approved 2022.05.09 · Insurance code 666300400

Summary

Main use
Improvement of hyperphosphatemia in patients with chronic kidney disease undergoing hemodialysis
Who takes it
Adults
Adult dose
Adults This product should be taken 3 times daily with meals or immediately after meals. The recommended initial dose of this product is 4 g daily. Adjust the dose in increments of 1 g (2 capsules) according to the serum phosphate concentration until the target serum phosphate concentration is reached, and monitor regularly thereafter. Adjust the dose at intervals of 1 week or longer. The maximum dose of this product is 6 g daily.

Ingredients

Importer
LG Chem Ltd.

Efficacy & effects

Improvement of hyperphosphatemia in patients with chronic kidney disease undergoing hemodialysis

  • Hyperphosphatemia
View approved original text

Used effectively to improve hyperphosphatemia in patients with chronic kidney disease undergoing hemodialysis.

How to take

Adult dose

Adults This product should be taken 3 times daily with meals or immediately after meals. The recommended initial dose of this product is 4 g daily. Adjust the dose in increments of 1 g (2 capsules) according to the serum phosphate concentration until the target serum phosphate concentration is reached, and monitor regularly thereafter. Adjust the dose at intervals of 1 week or longer. The maximum dose of this product is 6 g daily.

Precautions

This medication can lead to serious poisoning and death if a child accidentally takes a large amount, so it must be stored in a safe place out of reach of children. It should not be used in patients with allergies to this drug or its components, or those with certain conditions such as hypophosphatemia and iron overload. Use with caution if iron overload is suspected, and discontinue use immediately if symptoms of iron overload occur. Patients with gastrointestinal diseases or chronic hepatitis, as well as certain blood disorders, should exercise caution when using this medication. It should be administered carefully to patients with allergies to certain ingredients or a history of allergies. During treatment, changes in stool color or gastrointestinal symptoms such as constipation, abdominal pain, or diarrhea may occur, and these symptoms are relatively commonly reported. Regular blood tests and liver function tests should be conducted, and indicators related to iron levels should be periodically checked. Care should be taken not to take this medication with other iron preparations due to the risk of iron overload. This medication may interact with certain drugs, so consult a doctor or pharmacist if you are taking other medications. Women who are pregnant or breastfeeding should carefully consider the therapeutic benefits and risks before using this medication. The safety and efficacy in children have not been sufficiently confirmed, so use is generally discouraged except in special cases. Elderly patients may have decreased bodily functions, thus careful monitoring and cautious administration are necessary. Finally, this medication must be stored out of reach of children, and transferring it to another container can lead to accidents or deterioration of quality, so caution is advised.

Side effects

  • Stool discoloration
  • constipation
  • abdominal bloating
  • diarrhea
  • abdominal pain
  • upper abdominal pain
  • upper respiratory infection
  • nasopharyngitis
  • muscle spasm
  • cough
Show 9 more
  • procedure-related hypotension
  • shunt dysfunction
  • pruritus
  • dizziness
  • headache
  • hypotension
  • fever
  • hyperferritinemia
  • loose stools

Not everyone experiences these, and they can vary from person to person.

Storage

Store this medication at room temperature between 1°C and 30°C, and it is important to keep it in a tightly sealed container to prevent air and moisture entry. This way, the medication's effectiveness can be maintained for a longer period.

Appearance and packaging

Appearance

Hard capsule with red-brown upper and lower parts containing a light brown or light yellow-brown powder

Package unit

Bottle - 45 capsules/bottle, Bottle - 90 capsules/bottle

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.