Ibupipen Primix Injection (Ibuprofen)

Adult dosage

For the control of moderate to severe pain as an adjuvant to narcotic analgesics (morphine), administer 400 mg-800 mg intravenously every 6 hours as needed. The maximum daily dose is 3200 mg, and administration times should be at least 30 minutes. For fever, administer 400 mg intravenously every 4-6 hours as needed, with interval adjustments following the initial dose of 400 mg based on patient condition.

Children's dosage

For fever in children aged 6 months to under 12 years, administer 10 mg/kg per dose (maximum 400 mg), intravenously every 4 to 6 hours as needed, with administration times of at least 10 minutes. 1 day.

This medication should be used with caution by those with cardiovascular diseases or risk factors, as serious cardiovascular issues such as myocardial infarction or stroke may occur. It presents a risk of serious gastrointestinal problems such as bleeding, ulcers, or perforation, particularly for older individuals or those taking it for extended periods, who should closely monitor for unusual symptoms. Individuals with a history of gastrointestinal ulcers or bleeding, or severe liver, kidney, or heart diseases should not take this medication. Those who have had allergic reactions to bronchial asthma or aspirin should not use this medication. Administration should be avoided during the last three months of pregnancy as it may harm the fetus. Patients with blood abnormalities or tendencies to bleed, reduced liver or kidney function, elderly individuals, pregnant or breastfeeding women should use this medication with caution and under a physician's guidance. This medication can cause a range of severe side effects, such as serious allergic reactions, skin rash, liver dysfunction, respiratory difficulties, and hematological issues. Seek medical consultation immediately if unusual symptoms arise. Do not take this medication concurrently with other non-steroidal anti-inflammatory drugs, and avoid exceeding the recommended doses. Patients with hypertension may experience elevated blood pressure when taking this medication, and should regularly monitor and manage their blood pressure. Patients with heart failure or edema may have worsened fluid retention, and caution is advised. Individuals with poor renal function may experience kidney damage if taking this medication in a dehydrated state, thus hydration and condition should be well managed. If liver dysfunction is suspected, discontinue use and undergo liver function testing. A blood test should evaluate anemia or platelet dysfunction, and patients at risk of bleeding should exercise particular caution. When used with aspirin, anticoagulants, diuretics, lithium, methotrexate, etc., the risk of side effects due to interactions may increase, so it is essential to discuss this with a doctor. After the 20th week of pregnancy, this medication may affect fetal kidney function and should only be used at the minimum effective dose for a short period if absolutely necessary. During breastfeeding, this medication may be transferred to breast milk and could affect the infant, so consider stopping breastfeeding or discontinuing the medication. It is advisable not to use this medication for infants under 6 months, as its safety has not been established. Elderly individuals face a higher risk of side effects due to declining physical functions, so dosages should be adjusted according to a doctor's instructions, and use should be cautious. In cases of overdose, symptoms may include dizziness, vomiting, liver dysfunction, kidney failure, and respiratory difficulties; prompt discontinuation and treatment at a medical institution are necessary.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash accompanied by high fever, blisters, skin peeling, painful mucous membranes of the mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, respiratory distress accompanied by cough and fever, yellowing of the skin or eyes (jaundice), pronounced lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis.

Mild side effects

• Nausea
• vomiting
• bloating
• headache
• diarrhea
• drowsiness
• dizziness
• depression
• loss of appetite
• thirst

This medication must be stored in a sealed container to prevent contact with air and should be kept at room temperature between 1 and 30 degrees Celsius. Proper storage maintains the effectiveness and prevents degradation of the medication.

Appearance

A transparent colorless to slightly yellow liquid filled in a polypropylene, multilayer film plastic container.

Package unit

104 mL/vial, 208 mL/vial