EMPLDM Met Tablet 5/1000 mg

Adult dose

The recommended dose of this medication is 1 tablet, twice daily. The dosage should not exceed the total of 25 mg of empagliflozin and 2000 mg of metformin. For patients using metformin alone or in combination with other medications, the recommended dose is 5 mg of empagliflozin twice daily, along with the existing metformin dose. If tolerance is good, the dose of empagliflozin can be increased from 10 mg to 25 mg. This medication should be taken with food.

This medication helps to regulate blood sugar. However, it is important to adhere to various precautions when taking this medication. Firstly, this medication may cause a rare side effect known as severe lactic acidosis, which can be life-threatening, so caution is warranted. Lactic acidosis is a condition that occurs when there is an excessive accumulation of lactic acid in the body, with symptoms including malaise, muscle aches, difficulty breathing, weakness, and abdominal pain. In addition, when taken with insulin or sulfonylurea, there is a risk of hypoglycemia, so it’s important to be aware of hypoglycemic symptoms. Symptoms of hypoglycemia include dizziness, cold sweat, trembling, and headache. Patients with moderate to severe renal dysfunction, acute kidney problems, severe infections, unstable heart function, type 1 diabetes, and pregnant or breastfeeding women should not use this medication. This medication can affect kidney function, so regular kidney function tests should be conducted before and during treatment. Extreme caution is also advised during episodes of dehydration or severe vomiting and diarrhea, as these can increase the risk of worsening kidney function. The use of iodinated contrast media before and after certain examinations requires a temporary discontinuation of this medication, and it should be resumed only after confirming normal kidney function. During the course of this medication, urinary tract or genital infections may occur; hence, any signs of infection must be reported to healthcare providers immediately. Gastrointestinal disturbances (such as diarrhea, nausea, vomiting), skin rash, itching, increased urination, fluid loss, hypoglycemia, vitamin B12 deficiency, and other adverse reactions may occur; any abnormal symptoms should be discussed with a healthcare professional. Consumption of alcohol may increase the risk of side effects associated with this medication; therefore, alcohol should be avoided during use. Elderly patients or those with impaired kidney function should be especially cautious and require dose adjustments and regular monitoring. Pregnant women or those who may become pregnant, as well as breastfeeding women, should not take this medication, and alternative treatments should be considered if necessary. In case of overdose, serious side effects may occur, so the prescribed dose must be strictly adhered to, and immediate medical attention should be sought in the event of an overdose. It is essential to regularly monitor blood sugar and kidney function during the course of this medication. Additionally, consult a healthcare professional regarding possible interactions with other drugs when taking this medication.

Serious side effects

• Urticaria
• angioedema
• perineal necrosis
• ketoacidosis
• lactic acidosis
• pyelonephritis
• urosepsis
• liver dysfunction (jaundice)
• acute kidney injury
• acute cholecystitis

Mild side effects

• Hypoglycemia
• urinary tract infection
• genital infection
• increased urination
• nausea
• vomiting
• diarrhea
• abdominal pain
• loss of appetite
• constipation

This medication should be stored in a sealed container to avoid exposure to air or moisture. The recommended storage temperature is at room temperature between 1°C and 30°C.

Appearance

Biconvex oval film-coated tablet that is yellow with a brownish tint

Package unit

10 tablets/box [10 tablets/PTP × 1], 60 tablets/box [10 tablets/PTP × 6], 30 tablets/bottle, 60 tablets/bottle